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继发于鞍区曲霉脓肿酷似垂体肿瘤的继发性头痛:病例报告及文献复习

Secondary headache due to aspergillus sellar abscess simulating a pituitary neoplasm: case report and review of literature.

作者信息

Hong Wenyao, Liu Yuqing, Chen Mingwu, Lin Kun, Liao Zhengjian, Huang Shengyue

机构信息

Department of Neurosurgery, Fujian Provincial Hospital, Fujian Medical University, 134 Dongjie Road, Gulou District, Fuzhou, 350001 China.

出版信息

Springerplus. 2015 Sep 24;4:550. doi: 10.1186/s40064-015-1343-6. eCollection 2015.

Abstract

Fungal sellar abscess is rare. A 42-year-old man was admitted with 2-month headache characterized by right peri-orbital pain. An intrasellar mass was found to be simulated a pituitary neoplasm after magnetic resonance imaging examination, and operated on via an endoscopic trans-sphenoidal approach. Milk-like pus and a mass of ash black mixed and necrotic material were found and removed. Histopathology revealed numerous aspergillus hyphae. Itraconazole was given on a dosage of 200 mg twice a day orally for 6 weeks. No recurrence was observed during follow-up. Complete surgical resection through endoscopic trans-sphenoidal approach combined with systemic anti-fungal therapy, should be considered as the optimal treatment.

摘要

真菌性鞍区脓肿罕见。一名42岁男性因持续2个月的头痛入院,其特征为右侧眶周疼痛。磁共振成像检查后发现鞍内有一肿块,疑似垂体肿瘤,遂通过内镜经蝶窦入路进行手术。术中发现并清除了乳状脓液及一团灰黑色混合坏死物质。组织病理学检查显示有大量曲霉菌菌丝。给予伊曲康唑口服,剂量为每日2次,每次200mg,共6周。随访期间未观察到复发。经内镜经蝶窦入路完全切除联合全身抗真菌治疗应被视为最佳治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/038b/4582039/cfd5ed9d92d1/40064_2015_1343_Fig1_HTML.jpg

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