Cardoso Gerusa O M, Matta-Neto Edgard, El Achkar Vivian N R, Niccoli-Filho Walter
Department of Bioscience and Oral Diagnosis, Sao Paulo State University-UNESP, Sao Jose dos Campos, Sao Paulo, Brazil.
Department of Bioscience and Oral Diagnosis, Sao Paulo State University-UNESP, Sao Jose dos Campos, Sao Paulo, Brazil
J Surg Case Rep. 2013 Jul 23;2013(7):rjt044. doi: 10.1093/jscr/rjt044.
Keratocystic odontogenic tumour (KCOT) previously known as odontogenic keratocyst was recently classified as a benign lesion characterized by an infiltrating pattern, local aggressiveness with the propensity to recurrence. It is thought to arise from the dental lamina. Pain is usually not associated with KCOT until swelling occurs, and it commonly affects the posterior mandible. Multiple KCOT are associated with nevoid basal cell carcinoma syndrome. This study reports an aggressive case of KCOT with destruction of the osseous tissue of the mandible, accentuated face asymmetry, dysphagia and dysphonia. It was managed with a defined protocol which entailed diagnosis, treatment with enucleation along with peripheral ostectomy and rehabilitation. A long-term follow-up schedule was provided to the patient to observe the recurrence behaviour of this cyst. In postoperative phase, no complication was noticed regarding wound healing and recurrence.
角化囊性牙源性肿瘤（KCOT）以前称为牙源性角化囊肿，最近被归类为一种良性病变，其特征为浸润性生长方式、局部侵袭性以及易于复发。它被认为起源于牙板。在肿胀发生之前，疼痛通常与KCOT无关，并且它通常累及下颌骨后部。多发性KCOT与痣样基底细胞癌综合征相关。本研究报告了1例侵袭性KCOT病例，该病例导致下颌骨骨质破坏、面部不对称加剧、吞咽困难和发音困难。采用了一套明确的方案进行处理，该方案包括诊断、刮除术联合周边骨切除术治疗以及康复。为患者制定了长期随访计划，以观察该囊肿的复发情况。术后阶段，未发现伤口愈合和复发方面的并发症。
