Kakarantza-Angelopoulou E, Nicolatou O
Department of Oral Pathology, School of Dentistry, University of Athens, Greece.
J Oral Maxillofac Surg. 1990 Jun;48(6):593-9; discussion 599-600. doi: 10.1016/s0278-2391(10)80472-0.
The clinical and histologic features of 87 cases of odontogenic keratocysts were reviewed. Males were affected more frequently than females. All age groups were affected, with a predilection for the fifth and sixth decades. The molar-angle-ramus area of the mandible was the most common location (29.8%). In 7 cases (8.8%), the cysts were part of the basal cell nevus syndrome. Recurrences were observed in 9 cases (10.4%). The cysts were lined by a thin, regular, stratified squamous, parakeratinized epithelium without rete ridges. Orthokeratin was observed in 24.14% of the cases. Mitotic figures were observed in approximately 50% of the cases. Separation of lining epithelium from underlying connective tissue was observed in 82.7%, with subepithelial hyalinization in 75.8% of the cases. Inflammation was observed in 72.4%, cholesterol clefts were observed in 11.5%, and Rushton hyaline bodies in 4.6% of the cases. Dental lamina rests were observed in 32.2% and satellite cysts in 20.7%. Dystrophic calcifications were found in 36.8%. Ameloblastomatous proliferation was observed in 2 cases.
回顾了87例牙源性角化囊肿的临床和组织学特征。男性受累比女性更常见。所有年龄组均受累，以五、六十岁最为常见。下颌磨牙-角-升支区是最常见的部位（29.8%）。7例（8.8%）囊肿是基底细胞痣综合征的一部分。9例（10.4%）观察到复发。囊肿内衬一层薄的、规则的、分层鳞状、不全角化上皮，无上皮嵴。24.14%的病例观察到正角化。约50%的病例观察到有丝分裂象。82.7%观察到内衬上皮与下方结缔组织分离，75.8%的病例有上皮下玻璃样变。72.4%观察到炎症，11.5%观察到胆固醇裂隙，4.6%观察到鲁什顿透明小体。32.2%观察到牙板残余，20.7%观察到卫星囊肿。36.8%发现营养不良性钙化。2例观察到成釉细胞瘤样增生。
