Jesić Milana Poznić, Zivanović' Olga, Nikolić Igor, Radovanović Sasa, Sakić Branislav, Jesić Aleksandar
Med Pregl. 2014 Jan-Feb;67(1-2):28-32.
Deep brain stimulation is a stereotactic neurosurgical method used in the treatment of Parkinson's disease and some other movement disorders. The application of deep brain stimulation in the treatment of certain psychiatric disorders has been intensively investigated taking into account the current knowledge of neurobiological basis of mood regulation, cognition, and behaviour. This paper has been aimed at presenting the available data on experience in the application of deep brain stimulation in the treatment of psychiatric disorders. It gives an overview of scientific and professional literature, bearing in mind all the contemporary approaches in the treatment of certain psychiatric disorders. Research results available so far in the treatment of treatment-resistant depression, obsessive-compulsive disorder, Gilles de la Tourette syndrome, addiction and Alzheimer's dementia, are affirmative concerning the efficacy of the method and low risk of adverse effects. Deep brain stimulation, as a relatively new neurosurgical method in the treatment of psychiatric disorders, is being intensively developed, and it is certainly going to be one of the treatments of choice, primarily of treatment-resistant disorders.
深部脑刺激是一种用于治疗帕金森病和其他一些运动障碍的立体定向神经外科方法。考虑到目前关于情绪调节、认知和行为的神经生物学基础的知识，深部脑刺激在某些精神疾病治疗中的应用已得到深入研究。本文旨在介绍深部脑刺激在精神疾病治疗应用中的现有经验数据。它概述了科学和专业文献，同时考虑到当前治疗某些精神疾病的所有方法。迄今为止，在治疗难治性抑郁症、强迫症、抽动秽语综合征、成瘾和阿尔茨海默病性痴呆方面的研究结果，肯定了该方法的疗效和低不良反应风险。深部脑刺激作为一种治疗精神疾病的相对较新的神经外科方法，正在得到深入发展，并且肯定会成为主要针对难治性疾病的首选治疗方法之一。
