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[全胃肠外营养在膀胱浸润性肿瘤根治性膀胱切除术患者中的应用临床经验]

[Clinical experience on the use of total parenteral nutrition in patients subjected to radical cystectomy intervention for infiltrating neoplasms of the bladder].

作者信息

Del Boca C, Furiosi D, Bolis C, Ferrari C

出版信息

Arch Ital Urol Nefrol Androl. 1989 Mar;61(1):69-75.

PMID:2496468
Abstract

The Authors report their 7 year follow-up on the use of T.P.N. in 28 patients treated surgically for infiltrating cancer of the bladder. They consider the pathogenetic mechanisms that influence the organism's adaptation to surgical stress with particular reference to the multiple neuroendocrinal and biochemical interconnections. The procedures to define the nutritional/metabolic levels, of the patients undergoing operation are exposed. The T.P.N. is given according to the personal requirements of each patient and is a function of the "performance status", caloric need and to the presence of sepsis. Problems concerning the radical cistectomy such as: time of surgery, extention of exeresis, uroentheroanastomosis, metabolic variations, sepsis, etc., are evaluated. Considering the positive results obtained with this nutritional procedure, the Authors underline the importance of a systematic use of T.P.N. wich should be included, in their opinion, in a multidisciplinar treatment of advanced bladder neoplasms.

摘要

作者报告了对28例因浸润性膀胱癌接受手术治疗患者使用全胃肠外营养(TPN)的7年随访情况。他们考虑了影响机体适应手术应激的发病机制,特别提及了多种神经内分泌和生化联系。阐述了确定手术患者营养/代谢水平的程序。TPN根据每位患者的个人需求给予,是“身体状况”、热量需求和是否存在败血症的函数。评估了根治性膀胱切除术相关的问题,如:手术时间、切除范围、输尿管肠吻合术、代谢变化、败血症等。考虑到这种营养方法取得的积极成果,作者强调了系统使用TPN的重要性,他们认为TPN应纳入晚期膀胱肿瘤的多学科治疗中。

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