Yoshida K, Uchijima Y, Saitoh H
Department of Urology, Saitama Medical Center, Japan.
Urology. 1989 May;33(5):395-8. doi: 10.1016/0090-4295(89)90033-2.
To investigate whether or not transferrin production is decreased in the testis of idiopathic oligozoospermia, the seminal plasma transferrin concentration was measured and the values were compared in two groups (15 men of pregnancy-proved normozoospermia and 22 patients with idiopathic oligozoospermia). Seminal plasma transferrin concentration in the pregnancy-proved normozoospermic group was 78.5 +/- 37.9 micrograms/mL, and the concentration in the patients with idiopathic oligozoospermia was 44.4 +/- 37.6 micrograms/mL. There was a significant difference between them (P less than 0.01). The patients with idiopathic oligozoospermia could be divided into two subgroups according to seminal plasma transferrin concentration and serum gonadotropin levels. One group had high transferrin levels with elevated serum gonadotropin levels. The results indicate that the determination of seminal plasma transferrin concentration is one of the useful parameters for evaluation of testicular function and also suggest that additional studies may allow for the subdivision of the patients with so-called idiopathic oligozoospermia.
为了研究特发性少精子症患者睾丸中运铁蛋白的产生是否减少，我们检测了两组人群（15名经证实能使配偶怀孕的正常精子症男性和22例特发性少精子症患者）的精浆运铁蛋白浓度并比较其数值。经证实能使配偶怀孕的正常精子症组精浆运铁蛋白浓度为78.5±37.9微克/毫升，特发性少精子症患者组的浓度为44.4±37.6微克/毫升。两组之间存在显著差异（P<0.01）。特发性少精子症患者可根据精浆运铁蛋白浓度和血清促性腺激素水平分为两个亚组。一组运铁蛋白水平高且血清促性腺激素水平升高。结果表明，精浆运铁蛋白浓度的测定是评估睾丸功能的有用参数之一，也表明进一步的研究可能有助于对所谓的特发性少精子症患者进行细分。
