Alexiou Konstantinos, Ioannidis Argyrios, Drikos Ioannis, Fotopoulos Athanasios, Karanikas Ioannis, Economou Nikolaos
Department of Surgery, Sismanoglion General Hospital, Sismanoglou 1, P,O, Box 15126, Athens, Greece.
J Med Case Rep. 2014 Jun 25;8:228. doi: 10.1186/1752-1947-8-228.
Lesions of the ampulla of Vater are rare histological entities with an incidence of between 0.1 and 0.2% of gastrointestinal tumors. Until recently the main response to this kind of lesion was duodenopancreatectomy, regardless of the cellular atypia and local edema. In this study, we propose the application of transduodenal local excision of the ampulla of Vater especially in recognized cases of nonmalignant adenomas.
In this case report we analyze the case of a 78-year-old Greek man who revealed symptoms such as icterus, abdominal pain without constipation and bloody stools. A physical examination showed painless swelling of the gallbladder (Courvoisier sign). No previous abdominal operations or hernias were identified. Blood tests, computed tomography scan analysis, gastroscopy and endoscopic retrograde cholangiopancreatography along with biopsies and cytological tests diagnosed nonmalignant adenoma of the ampulla of Vater with high-grade dysplasia. The treatment we followed was transduodenal local excision of his ampulla of Vater.
Transduodenal local excision of the ampulla of Vater has limited side effects and postoperative complications, suggesting this particular technique to be the proper treatment for nonmalignant cases of adenomas.
Vater壶腹病变是罕见的组织学实体,在胃肠道肿瘤中发生率为0.1%至0.2%。直到最近,对于这类病变的主要治疗方法是十二指肠胰切除术,而不考虑细胞异型性和局部水肿情况。在本研究中,我们提议对Vater壶腹进行经十二指肠局部切除术,尤其是在已确诊的非恶性腺瘤病例中。
在本病例报告中,我们分析了一名78岁希腊男性的病例,该患者出现黄疸、无便秘的腹痛和便血等症状。体格检查显示胆囊无痛性肿大(Courvoisier征)。既往无腹部手术史或疝气。血液检查、计算机断层扫描分析、胃镜检查和内镜逆行胰胆管造影以及活检和细胞学检查诊断为Vater壶腹非恶性腺瘤伴高级别异型增生。我们采用的治疗方法是对其Vater壶腹进行经十二指肠局部切除术。
经十二指肠局部切除Vater壶腹的副作用和术后并发症有限,表明这种特殊技术是腺瘤非恶性病例的合适治疗方法。