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补充维生素D可改善暴露于静磁场的大鼠的低胰岛素血症和高血糖症。

Vitamin D supplementation ameliorates hypoinsulinemia and hyperglycemia in static magnetic field-exposed rat.

作者信息

Lahbib Aïda, Ghodbane Soumaya, Maâroufi Karima, Louchami Karim, Sener Abdullah, Sakly Mohsen, Abdelmelek Hafedh

机构信息

a Laboratory of Integrative Physiology, Faculty of Sciences of Bizerte, Cathage University , Jarzouna , Tunisia.

出版信息

Arch Environ Occup Health. 2015;70(3):142-6. doi: 10.1080/19338244.2013.828675.

Abstract

The purpose of this study is to evaluate the effects of vitamin D supplementation on glucose and lipid metabolism in static magnetic field (SMF)-exposed rats. Rats exposed to SMF (128 mT; 1 h/day) during 5 consecutive days showed an increase in plasma glucose level and a decrease in plasma insulin concentration. By contrast, the same treatment failed to alter body weight and plasmatic total cholesterol, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, and triglyceride levels. Interestingly, supplementation with vitamin D (1,600 IU/100 g, per os) corrected and restored glycemia and insulinemia in SMF-exposed rats. The same treatment had no effects on lipid metabolism.

摘要

本研究的目的是评估补充维生素D对暴露于静磁场(SMF)的大鼠葡萄糖和脂质代谢的影响。连续5天暴露于SMF(128 mT;每天1小时)的大鼠血浆葡萄糖水平升高,血浆胰岛素浓度降低。相比之下,相同处理未能改变体重以及血浆总胆固醇、高密度脂蛋白(HDL)胆固醇、低密度脂蛋白(LDL)胆固醇和甘油三酯水平。有趣的是,补充维生素D(1600 IU/100 g,经口)可纠正并恢复暴露于SMF的大鼠的血糖和胰岛素血症。相同处理对脂质代谢无影响。

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