一例伴8号染色体三体的慢性中性粒细胞白血病
A case of chronic neutrophilic leukemia with trisomy 8.
作者信息
Orazi A, Cattoretti G, Sozzi G
机构信息
Division of Anatomic Pathology and Cytopathology, National Tumor Institute, Milan, Italy.
出版信息
Acta Haematol. 1989;81(3):148-51. doi: 10.1159/000205548.
PMID:2496562
Abstract
The authors describe a case of chronic neutrophilic leukemia (CNL) showing trisomy of chromosome 8. This anomaly, particularly common in cases of myelodysplastic syndrome (MDS), has never been previously found to be associated with this rare type of leukemia. Thus CNL may occasionally be cytogenetically indistinguishable from cases of MDS.
摘要
作者描述了一例显示8号染色体三体的慢性中性粒细胞白血病（CNL）病例。这种异常在骨髓增生异常综合征（MDS）病例中尤为常见，此前从未发现与这种罕见类型的白血病相关。因此，CNL在细胞遗传学上偶尔可能与MDS病例难以区分。
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