Lahav M, Rosenberg I, Wysenbeek A J
Department of Internal Medicine, Beilinson Medical Center, Petah Tiqva, Israel.
Acta Haematol. 1989;81(3):166-8. doi: 10.1159/000205552.
We report a case of idiopathic cold agglutinin disease (ICAD) that responded well to corticosteroid therapy, though generally these patients show no response to such therapy. The cold agglutinins in this patient were found to be of low titer (1:32) and wide thermal range (4-37 degrees C). Three patients with ICAD were previously reported, also responsive to corticosteroid therapy and having the same characteristics of their autoantibodies. are likely to respond to corticosteroid therapy and that a therapeutic trial with such agents is warranted in these patients.
我们报告一例特发性冷凝集素病（ICAD），该病例对皮质类固醇治疗反应良好，尽管一般来说这些患者对这种治疗无反应。该患者的冷凝集素效价较低（1:32）且热范围较宽（4 - 37摄氏度）。之前报道过3例ICAD患者，也对皮质类固醇治疗有反应且其自身抗体具有相同特征。这些患者可能对皮质类固醇治疗有反应，因此有必要对这些患者进行此类药物的治疗试验。
