利用个体住房数据的新型社会经济衡量指标在哮喘研究中的应用：一项探索性研究。
Application of a novel socioeconomic measure using individual housing data in asthma research: an exploratory study.
机构信息
Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.
Mercy Clinic, Springfield, MO, USA.
出版信息
NPJ Prim Care Respir Med. 2014 Jun 26;24:14018. doi: 10.1038/npjpcrm.2014.18.
BACKGROUND
A housing-based socioeconomic index (HOUSES) was previously developed to overcome an absence of socioeconomic status (SES) measures in common databases. HOUSES is associated with child health outcomes in Olmsted County, Minnesota, USA, but generalisability to other geographic areas is unclear.
AIM
To assess whether HOUSES is associated with asthma outcomes outside Olmsted County, Minnesota, USA.
METHODS
Using a random sample of children with asthma from Sanford Children's Hospital, Sioux Falls, SD, USA, asthma status was determined. The primary outcome was asthma control status using Asthma Control Test and a secondary outcome was risk of persistent asthma. Home address information and property data were merged to formulate HOUSES. Other SES measures were examined: income, parental education (PE), Hollingshead and Nakao-Treas index.
RESULTS
Of a random sample of 200 children, 80 (40%) participated in the study. Of those, 13% had poorly controlled asthma. Addresses of 94% were matched with property data. HOUSES had moderate-good correlation with other SES measures except PE. Poor asthma control rates were 31.6%, 4.8% and 5.6% for patients in the lowest, intermediate and highest tertiles of HOUSES, respectively (P=0.023). HOUSES as a continuous variable was inversely associated with poorly controlled asthma (adjusted odds ratio (OR)=0.21 per 1 unit increase of HOUSES, 95% confidence interval (CI), 0.05-0.89, P=0.035). HOUSES as a continuous variable was inversely related to risk of persistent asthma (OR: 0.36 per 1 unit increase of HOUSES, 95% CI, 0.12-1.04, P=0.06).
CONCLUSIONS
HOUSES appears to be generalisable and available as a measure of SES in asthma research in the absence of conventional SES measures.
背景
先前开发了一种基于住房的社会经济指数（HOUSES），以克服常见数据库中缺乏社会经济地位（SES）衡量标准的问题。HOUSES 与美国明尼苏达州奥姆斯特德县的儿童健康结果有关，但在其他地理区域的适用性尚不清楚。
目的
评估 HOUSES 是否与美国明尼苏达州奥姆斯特德县以外的哮喘结果有关。
方法
使用来自美国南达科他州苏福尔斯桑福德儿童医院的哮喘儿童随机样本，确定哮喘状况。主要结果是使用哮喘控制测试（Asthma Control Test）评估哮喘控制状况，次要结果是持续性哮喘的风险。合并家庭地址信息和财产数据以制定 HOUSES。还检查了其他 SES 衡量标准：收入、父母教育（PE）、霍林斯黑德和中尾-特雷索指数。
结果
在随机抽取的 200 名儿童中，有 80 名（40%）参与了研究。其中，13%的儿童哮喘控制不佳。94%的地址与财产数据相匹配。HOUSES 与其他 SES 衡量标准除 PE 外均具有中等良好的相关性。在 HOUSES 最低、中、高三分位数的患者中，哮喘控制不佳的比例分别为 31.6%、4.8%和 5.6%（P=0.023）。HOUSES 作为一个连续变量与哮喘控制不佳呈负相关（调整后的优势比（OR）=每增加 1 个单位的 HOUSES 则为 0.21，95%置信区间（CI），0.05-0.89，P=0.035）。HOUSES 作为一个连续变量与持续性哮喘的风险呈负相关（OR：每增加 1 个单位的 HOUSES 则为 0.36，95%CI，0.12-1.04，P=0.06）。
结论
在缺乏常规 SES 衡量标准的情况下，HOUSES 似乎是可推广的，并且可作为哮喘研究中 SES 的衡量标准。
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