Goyal Rajeev, Kumar Ashok, Singhai Monil
Department of Biochemistry, Government Medical College, Haldwani, Uttarakhand India ; Department of Biochemistry, All India Institute of Medical Sciences, Rishikesh, 249201 Uttarakhand India.
Department of Medicine, Government Medical College, Haldwani, Uttarakhand India.
Indian J Clin Biochem. 2014 Jul;29(3):362-6. doi: 10.1007/s12291-013-0366-4. Epub 2013 Jul 28.
Metabolic syndrome is a complex of metabolic factors which includes central obesity, insulin-resistance, dyslipidemia and hypertension. Metabolic syndrome is associated with increased risk of cardiovascular disease. This study aimed to know the rate of metabolic syndrome in outpatients presenting to medicine department of our hospital and their profile. The metabolic syndrome was diagnosed using International Diabetes Federation criteria. The parameters analyzed included age, sex, blood pressure, BMI, fasting plasma glucose, HDL and triglycerides. The rate of metabolic syndrome was 21.1 % in our study. The younger population was most susceptible to metabolic derangements. Further, females were found to be affected more than males. The extremely significant parameters were deranged fasting plasma glucose, HDL, triglycerides while hypertension was found to be insignificant. Being overweight maybe a strong predictor for presence of metabolic syndrome in our region of study, and all overweight persons should be assessed and appropriately treated to prevent future cardiovascular events.
代谢综合征是一组代谢因素的综合体，包括中心性肥胖、胰岛素抵抗、血脂异常和高血压。代谢综合征与心血管疾病风险增加相关。本研究旨在了解我院内科门诊患者的代谢综合征发生率及其特征。代谢综合征采用国际糖尿病联盟标准进行诊断。分析的参数包括年龄、性别、血压、体重指数、空腹血糖、高密度脂蛋白和甘油三酯。在我们的研究中，代谢综合征的发生率为21.1%。较年轻人群最易出现代谢紊乱。此外，发现女性受影响的程度大于男性。极为显著的参数是空腹血糖紊乱、高密度脂蛋白、甘油三酯，而高血压则无显著意义。在我们的研究区域，超重可能是代谢综合征存在的一个强有力的预测因素，所有超重者都应接受评估并进行适当治疗，以预防未来的心血管事件。
