Diabetes Research Unit, Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.
Diabetol Metab Syndr. 2012 May 31;4(1):24. doi: 10.1186/1758-5996-4-24.
Metabolic Syndrome (MS) increases the risk for Coronary Artery Disease, stroke and diabetes. MS is twice more common amongst South Asian immigrants in US compared to native Caucasians. There are no nationally representative studies on prevalence of MS from any of the South Asian countries. The present study aims to evaluate the prevalence of MS among Sri Lankan adults and investigates its relationships with socio-demographic, clinical and biochemical parameters. Data on MS and its associated details were obtained from a population-based cross-sectional study conducted between years 2005-2006. MS was defined according to the International Diabetes Federation criteria. A binary logistic regression analysis was performed using the dichotomous variable MS (0 = absent, 1 = present). The independent co-variants were: gender, age category, area of residence, ethnicity, level of education, income and physical activity. Sample size was 4,485 (Response rate-89.7%), 39.5% were males and mean age was 46.1 ± 15.1 years. The crude prevalence of MS was 27.1% (95% CI: 25.8-28.5), and age-adjusted prevalence was 24.3% (95% CI: 23.0-25.6). Prevalence in males and females were 18.4% (95% CI: 16.5-20.3) and 28.3% (95% CI: 26.6-30.0) respectively (p < 0.001). Urban adults (34.8% [95% CI: 31.8-37.9]) had a significantly higher prevalence than rural adults (21.6% [95% CI: 20.2-23.0]). Among ethnic groups, the highest prevalence of MS was observed in Sri Lankan Moors (43.0% [95% CI: 37.2-48.9]). In all adults, MS was observed in those with the highest level of education and monthly household income. Prevalence of MS in the different physical activity categories of the IPAQ were; 'inactive'-38.8% (95% CI 34.5-43.2), 'moderately active'-33.5% (95% CI 30.9-36.1) and 'active'-21.1% (95% CI 19.6-22.7). The results of the binary logistic regression analysis indicates that female gender (OR:1.7), increasing age, urban living (OR:1.7), Moor ethnicity (OR:2.6), secondary (OR:1.5) and tertiary levels of education (OR:2.3), monthly household income LKR 7,000-24,999 (OR:1.5) and >50,000 (OR:2.1), and physical inactivity (OR:1.6), all significantly increased risk of developing MS. MS is common among Sri Lankan adults affecting nearly one-fourth of the population. Female gender, increasing age, urban living, higher socio-economical status and physical inactivity were important associated factors.
代谢综合征（MS）会增加患冠状动脉疾病、中风和糖尿病的风险。与美国本土白种人相比，南亚移民患 MS 的风险要高出两倍。目前，还没有来自任何南亚国家的关于 MS 患病率的全国代表性研究。本研究旨在评估斯里兰卡成年人中 MS 的患病率，并调查其与社会人口统计学、临床和生化参数的关系。MS 及其相关细节的数据来自于 2005-2006 年间进行的一项基于人群的横断面研究。根据国际糖尿病联合会的标准定义 MS。使用二分类变量 MS（0=不存在，1=存在）进行二元逻辑回归分析。独立协变量为：性别、年龄组、居住区域、种族、教育水平、收入和体力活动。样本量为 4485 人（应答率-89.7%），其中 39.5%为男性，平均年龄为 46.1±15.1 岁。MS 的粗患病率为 27.1%（95%CI：25.8-28.5），年龄调整后的患病率为 24.3%（95%CI：23.0-25.6）。男性和女性的患病率分别为 18.4%（95%CI：16.5-20.3）和 28.3%（95%CI：26.6-30.0）（p<0.001）。城市成年人（34.8%[95%CI：31.8-37.9]）的患病率明显高于农村成年人（21.6%[95%CI：20.2-23.0]）。在不同种族群体中，MS 的患病率最高的是斯里兰卡摩尔人（43.0%[95%CI：37.2-48.9]）。在所有成年人中，MS 见于受教育程度和家庭月收入最高的人群。国际体力活动问卷（IPAQ）不同体力活动类别的 MS 患病率分别为：“不活动”-38.8%（95%CI 34.5-43.2），“适度活动”-33.5%（95%CI 30.9-36.1）和“活跃”-21.1%（95%CI 19.6-22.7）。二元逻辑回归分析的结果表明，女性（OR：1.7）、年龄增长、城市居住（OR：1.7）、摩尔族裔（OR：2.6）、中学（OR：1.5）和高等教育（OR：2.3）、家庭月收入 LKR 7000-24999（OR：1.5）和>LKR 50000（OR：2.1）以及缺乏体力活动（OR：1.6），所有这些因素都显著增加了患 MS 的风险。MS 在斯里兰卡成年人中很常见，影响了近四分之一的人口。女性、年龄增长、城市生活、较高的社会经济地位和缺乏体力活动是重要的相关因素。
