Endo F, Ishii T, Kito T
Dept. of Orthopaedic Surgery, School of Medicine, Chiba University.
Gan To Kagaku Ryoho. 1989 Apr;16(4 Pt 1):851-4.
A 51-year-old female with advanced breast cancer involving multiple bone metastases was daily administered 400 mg of UFT and 20 mg of tamoxifen. X-ray examination revealed remarkable osteosclerosis. Laboratory data revealed a high serum alkali phosphatase level of 820 mU/ml(at 3 months), which gradually decreased to 274 mU/ml with pain relief at 11 months after the beginning of this chemotherapy.
一名51岁患有晚期乳腺癌并伴有多处骨转移的女性患者，每天服用400毫克优福定（UFT）和20毫克他莫昔芬。X线检查显示明显的骨质硬化。实验室数据显示血清碱性磷酸酶水平较高，开始化疗3个月时为820 mU/ml，在化疗开始11个月疼痛缓解时逐渐降至274 mU/ml。
