Olpin Jeffrey Dee, Witt Benjamin
Department of Radiology, University of Utah Health Sciences Center, Salt Lake City, USA.
Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, USA.
J Radiol Case Rep. 2014 Feb 1;8(2):46-53. doi: 10.3941/jrcr.v8i2.1489. eCollection 2014 Feb.
Congenital adrenal hyperplasia refers to a group of autosomal recessive disorders caused by a deficiency of an enzyme involved in the synthesis of glucocorticoids. The enzyme deficiency generally leads to a deficiency of cortisol and/or aldosterone production within the adrenal cortex. The lack of glucocorticoids generally leads to elevated levels of plasma corticotropin (ACTH), which often results in adrenal hyperplasia. Testicular adrenal rest tumors may develop in males with congenital adrenal hyperplasia due to overstimulation of aberrant adrenal cells within the testes. Recognition of this disease entity is essential when evaluating young males with testicular masses.
先天性肾上腺增生症是指一组由参与糖皮质激素合成的酶缺乏引起的常染色体隐性疾病。酶缺乏通常导致肾上腺皮质内皮质醇和/或醛固酮分泌不足。糖皮质激素缺乏通常会导致血浆促肾上腺皮质激素（ACTH）水平升高，这往往会导致肾上腺增生。先天性肾上腺增生症男性患者由于睾丸内异常肾上腺细胞受到过度刺激，可能会出现睾丸肾上腺残余肿瘤。在评估患有睾丸肿块的年轻男性时，识别这种疾病实体至关重要。
