先天性肾上腺皮质增生症中的睾丸肾上腺残余肿瘤
Testicular adrenal rest tumours in congenital adrenal hyperplasia.
作者信息
Claahsen-van der Grinten H L, Hermus A R M M, Otten B J
机构信息
Department of Paediatric Endocrinology (833), Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
出版信息
Int J Pediatr Endocrinol. 2009;2009:624823. doi: 10.1155/2009/624823. Epub 2009 Feb 26.
In adult patients with congenital adrenal hyperplasia (CAH), the presence of testicular adrenal rest tumours (TART) is an important complication leading to gonadal dysfunction and infertility. These tumours can be already found in childhood and puberty. In this paper, we review the embryological, histological, biochemical, and clinical features of TART and discuss treatment options.
在成年先天性肾上腺皮质增生症（CAH）患者中，睾丸肾上腺残余肿瘤（TART）的存在是导致性腺功能障碍和不育的重要并发症。这些肿瘤在儿童期和青春期即可发现。在本文中，我们综述了TART的胚胎学、组织学、生物化学和临床特征，并讨论了治疗方案。
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