Tang Ye-Lei, Shentu Xing-Chao, Zhao Su-Juan, Tang Xia-Jing, He Long, Ping Fei-Yun
Department of Neurology, Second Affiliated Hospital of the Medical College, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
Eye Center, Second Affiliated Hospital of the Medical College, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
Int J Ophthalmol. 2014 Jun 18;7(3):574-6. doi: 10.3980/j.issn.2222-3959.2014.03.32. eCollection 2014.
We report a case of syndromic gingival fibromatosis with notable ocular lesions, bilateral congenital cataracts, esotropia, and high myopia of a 21-year-old male patient from China. The patient was diagnosed with gingival fibromatosis based on his massive gingival overgrowth and histological findings that were consistent with gingival fibromatosis through a gingival biopsy. Lens opacity features were presented and phacoemulsificaion with intraocular lens(IOL) implantation was performed to manage the cataracts in both eyes. Transmission electronic microscopy was used to investigate the ultrastructure of the removed lens tissue. We also review the literature on gingival fibromatosis and briefly summarize the ocular manifestations of this rare disease.
我们报告了一例来自中国的21岁男性综合征性牙龈纤维瘤病患者，伴有明显的眼部病变、双侧先天性白内障、内斜视和高度近视。该患者因牙龈大量增生，经牙龈活检，组织学检查结果与牙龈纤维瘤病相符，被诊断为牙龈纤维瘤病。出现晶状体混浊特征，遂行双眼白内障超声乳化吸除联合人工晶状体植入术。采用透射电子显微镜观察切除的晶状体组织超微结构。我们还回顾了有关牙龈纤维瘤病的文献，并简要总结了这种罕见疾病的眼部表现。
