[针刺疗程背景下实验性胃溃疡大鼠下丘脑和脑干中多巴胺及多巴含量的研究]
[The DOPA and dopamine content in the hypothalamus and brain stem of rats with an experimental stomach ulcer against a background of a course of acupuncture].
作者信息
Emel'ianenko I V, Bragin E O
出版信息
Biull Eksp Biol Med. 1989 Mar;107(3):274-9.
In experiments on rats with experimental ulcer of the stomach (EUS) using spectrofluorometric method the increase of DOPA and dopamine (DA) in brain stem, has been revealed as well as DOPA in hypothalamus. Change of the level of DOPA takes place at an early stage of ulcer formation. Acupuncture (AP) inserts essential corrections into the distribution of catecholamines under study. So, the content of DOPA and DA in hypothalamus and particularly in the brain stem in rats with EUS against the background of AP sharply increases. It has been supposed that AP realizes its therapeutic influence during ulcer disease due to the alteration of catecholaminergic brain system.
在使用荧光分光光度法对患有实验性胃溃疡（EUS）的大鼠进行的实验中，已发现脑干中多巴（DOPA）和多巴胺（DA）以及下丘脑中的多巴有所增加。多巴水平的变化发生在溃疡形成的早期阶段。针刺（AP）对所研究的儿茶酚胺分布进行了重要调节。因此，在针刺背景下，患有EUS的大鼠下丘脑尤其是脑干中的多巴和多巴胺含量急剧增加。据推测，针刺在溃疡病期间发挥其治疗作用是由于儿茶酚胺能脑系统的改变。
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