使用滨蒿内酯O-脱甲基酶测定法对肝微粒体单加氧酶诱导剂类型进行分类。 - Suppr

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超能文献

Using the scoparone O-demethylase assay for categorizing types of hepatic microsomal monooxygenase inducers.

作者信息

Kato S, Yamamoto K

机构信息

School of Pharmacy, Hokuriku University, Kanazawa, Japan.

出版信息

Bull Environ Contam Toxicol. 1989 Apr;42(4):489-94. doi: 10.1007/BF01700226.

DOI:10.1007/BF01700226

PMID:2496779

Abstract

摘要

相似文献

Using the scoparone O-demethylase assay for categorizing types of hepatic microsomal monooxygenase inducers.使用滨蒿内酯O-脱甲基酶测定法对肝微粒体单加氧酶诱导剂类型进行分类。

Bull Environ Contam Toxicol. 1989 Apr;42(4):489-94. doi: 10.1007/BF01700226.

Scoparone O-demethylase assay is not useful to differentiate the effects of model inducers of cytochrome P-450 in rabbit and guinea pig liver.滨蒿内酯O-脱甲基酶测定对于区分细胞色素P-450模型诱导剂对兔和豚鼠肝脏的影响并无用处。

Life Sci. 1993;53(25):PL421-6. doi: 10.1016/0024-3205(93)90034-z.

Different responsiveness of hepatic and pulmonary microsomal mixed function oxidases to phenobarbital-type and 3-methylcholanthrene-type polychlorinated biphenyls in rats.大鼠肝脏和肺微粒体混合功能氧化酶对苯巴比妥型和3-甲基胆蒽型多氯联苯的不同反应性。

J Pharmacobiodyn. 1983 Dec;6(12):954-62. doi: 10.1248/bpb1978.6.954.

Polychlorinated biphenyls as phenobarbitone-type inducers of microsomal enzymes. Structure-activity relationships for a series of 2,4-dichloro-substituted congeners.多氯联苯作为微粒体酶的苯巴比妥型诱导剂。一系列2,4-二氯取代同系物的构效关系。

Biochem Pharmacol. 1983 Oct 1;32(19):2955-63. doi: 10.1016/0006-2952(83)90402-1.

Difference in the nature of induction of mixed-function oxidase systems of the rat liver among phenobarbital, DDT, 3-methylcholanthrene, and TCDD.苯巴比妥、滴滴涕、3-甲基胆蒽和四氯二苯并二恶英对大鼠肝脏混合功能氧化酶系统诱导性质的差异。

Toxicol Appl Pharmacol. 1981 Oct;61(1):109-18. doi: 10.1016/0041-008x(81)90012-0.

Induction of hepatic microsomal propranolol N-desisopropylase activity by 3-methylcholanthrene and Sudan III.3-甲基胆蒽和苏丹III对肝微粒体普萘洛尔N-去异丙基酶活性的诱导作用

Biochem Biophys Res Commun. 1982 Apr 14;105(3):1233-9. doi: 10.1016/0006-291x(82)91100-7.

Hepatic microsomal enzyme induction by 2,2', 3,3', 4,4'- and 2,2', 3', 4,4', 5-hexachlorobiphenyl.2,2',3,3',4,4'-六氯联苯和2,2',3',4,4',5-六氯联苯对肝微粒体酶的诱导作用

Life Sci. 1980 Dec 15;27(24):2333-7. doi: 10.1016/0024-3205(80)90502-0.

Hepatic and extrahepatic induction of drug-metabolizing enzymes in specific pathogen free and germ free rats.特定病原体-free和无菌大鼠肝脏及肝外药物代谢酶的诱导作用

Gen Pharmacol. 1979;10(3):239-47. doi: 10.1016/0306-3623(79)90096-x.

Species and congener specific induction of hepatic cytochrome P4504A by polychlorinated biphenyls.多氯联苯对肝脏细胞色素P4504A的种属及同系物特异性诱导作用。

Biochem Pharmacol. 1992 Feb 4;43(3):637-9. doi: 10.1016/0006-2952(92)90588-a.

Species differences in stimulation of intestinal and hepatic microsomal mixed-function oxidase enzymes.肠道和肝脏微粒体混合功能氧化酶的刺激作用中的物种差异。

Biochem Pharmacol. 1980 Apr 15;29(8):1161-5. doi: 10.1016/0006-2952(80)90412-8.

引用本文的文献

Differences in the effects of model inducers of cytochrome P450 on the biotransformation of scoparone in rat and hamster liver.细胞色素P450模型诱导剂对滨蒿内酯在大鼠和仓鼠肝脏中生物转化作用的差异。

Arch Toxicol. 1993;67(2):92-7. doi: 10.1007/BF01973677.

本文引用的文献

Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。

J Biol Chem. 1951 Nov;193(1):265-75.

O-demethylation of scoparone and studies on the scoparone-induced spectral change of cytochrome P-450 in rat liver microsomes.滨蒿内酯的O-去甲基化及滨蒿内酯诱导大鼠肝微粒体细胞色素P-450光谱变化的研究。

Hoppe Seylers Z Physiol Chem. 1981 Aug;362(8):1091-9. doi: 10.1515/bchm2.1981.362.2.1091.

Hepatic microsomal enzyme induction by 2,2', 3,3', 4,4'- and 2,2', 3', 4,4', 5-hexachlorobiphenyl.2,2',3,3',4,4'-六氯联苯和2,2',3',4,4',5-六氯联苯对肝微粒体酶的诱导作用

Life Sci. 1980 Dec 15;27(24):2333-7. doi: 10.1016/0024-3205(80)90502-0.

Sex difference in the O-dealkylation activity of 7-hydroxycoumarin O-alkyl derivatives in liver microsomes of rats.大鼠肝微粒体中7-羟基香豆素O-烷基衍生物O-脱烷基化活性的性别差异。

Biochem Pharmacol. 1980 Apr 1;29(7):1015-22. doi: 10.1016/0006-2952(80)90164-1.

Purification and characterization of cytochrome P-450 with high affinity for 7-alkoxycoumarins.对7-烷氧基香豆素具有高亲和力的细胞色素P-450的纯化与特性研究

J Biochem. 1984 May;95(5):1379-88. doi: 10.1093/oxfordjournals.jbchem.a134745.

The O-dealkylation of 7-ethoxycoumarin by liver microsomes. A direct fluorometric test.肝脏微粒体对7-乙氧基香豆素的O-脱烷基作用。一种直接荧光测定法。

Hoppe Seylers Z Physiol Chem. 1972 Jul;353(7):1171-7. doi: 10.1515/bchm2.1972.353.2.1171.

Polychlorinated biphenyls: synthesis of some individual chlorobiphenyls.多氯联苯：某些单氯联苯的合成

Bull Environ Contam Toxicol. 1971 May-Jun;6(3):209-19. doi: 10.1007/BF01539929.

Formation of a glutathione conjugate from butylated hydroxytoluene by rat liver microsomes.大鼠肝脏微粒体将丁基化羟基甲苯转化为谷胱甘肽共轭物。

Biochem Pharmacol. 1985 Jun 15;34(12):2109-14. doi: 10.1016/0006-2952(85)90403-4.

Gas chromatographic-mass spectrometric analysis of monodemethylated metabolites of 6,7- and 7,8-dimethoxycoumarin isomers.6,7-和7,8-二甲氧基香豆素异构体单去甲基代谢物的气相色谱-质谱分析

J Chromatogr. 1986 Jul 18;362(2):274-7. doi: 10.1016/s0021-9673(01)86976-4.

Inductive effect of polychlorinated biphenyls mixture and individual isomers on the hepatic microsomal enzymes.多氯联苯混合物及个别异构体对肝脏微粒体酶的诱导作用。

Chem Pharm Bull (Tokyo). 1978 Apr;26(4):1215-21. doi: 10.1248/cpb.26.1215.

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