Khoja Samannaaz S, Susko Allyn M, Josbeno Deborah A, Piva Sara R, Fitzgerald G Kelley
Department of Physical Therapy, School of Health & Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, PA, USA.
J Comp Eff Res. 2014 May;3(3):283-99. doi: 10.2217/cer.14.15.
Obesity is a well-known modifiable risk factor for osteoarthritis (OA) in weight-bearing joints, and is present in approximately 35% of individuals with OA. Obesity adds significant burden to individuals with OA and is associated with poorer functional status and greater disability. In addition to tackling OA-related impairments, such as pain and functional limitations, interventions in this population need to address bodyweight reduction, as well as promotion of active lifestyle behaviors. While exercise and regular physical activity participation are both recommended and beneficial for OA and obese populations, our current understanding of optimal strategies to improve function and health status in those who have both OA and obesity is limited. This review will summarize the current available evidence related to effectiveness of various physical activity interventions to reduce pain, improve function and overall health-related quality of life in overweight or obese individuals with OA.
肥胖是负重关节骨关节炎（OA）一个众所周知的可改变风险因素，约35%的OA患者存在肥胖问题。肥胖给OA患者增加了巨大负担，与较差的功能状态和更大的残疾相关。除了应对与OA相关的损伤，如疼痛和功能受限外，针对这一人群的干预措施还需要解决体重减轻问题，以及促进积极的生活方式行为。虽然运动和定期参与体育活动对OA患者和肥胖人群都有推荐且有益，但我们目前对改善同时患有OA和肥胖症患者的功能和健康状况的最佳策略的理解有限。本综述将总结目前现有的证据，这些证据与各种体育活动干预措施在减轻超重或肥胖OA患者疼痛、改善功能和整体健康相关生活质量方面的有效性有关。
