骨关节炎与糖尿病之间的联系：从体育活动角度看对管理的启示
Links between osteoarthritis and diabetes: implications for management from a physical activity perspective.
作者信息
Piva Sara R, Susko Allyn M, Khoja Samannaaz S, Josbeno Deborah A, Fitzgerald G Kelley, Toledo Frederico G S
机构信息
Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Bridgeside Point 1, 100 Technology Drive, Suite 210, Pittsburgh, PA 15219, USA.
Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, Bridgeside Point 1, 100 Technology Drive, Suite 210, Pittsburgh, PA 15219, USA.
出版信息
Clin Geriatr Med. 2015 Feb;31(1):67-87, viii. doi: 10.1016/j.cger.2014.08.019. Epub 2014 Oct 7.
Abstract
Osteoarthritis (OA) and type 2 diabetes mellitus (T2DM) often coexist in older adults. Those with T2DM are more susceptible to developing arthritis, which has been traditionally attributed to common risk factors, namely, age and obesity. Alterations in lipid metabolism and hyperglycemia might directly impact cartilage health and subchondral bone, contributing to the development/progression of OA. Adequate management of older persons with both conditions benefits from a comprehensive understanding of the associated risk factors. We discuss common risk factors and emerging links between OA and T2DM, emphasizing the importance of physical activity and the implications of safe and effective physical activity.
摘要
骨关节炎（OA）和2型糖尿病（T2DM）在老年人中常常并存。患有T2DM的人更容易患关节炎，传统上这归因于常见的风险因素，即年龄和肥胖。脂质代谢改变和高血糖可能直接影响软骨健康和软骨下骨，促进OA的发生/发展。对同时患有这两种疾病的老年人进行充分管理，需要全面了解相关风险因素。我们讨论OA和T2DM之间的常见风险因素及新出现的联系，强调身体活动的重要性以及安全有效的身体活动的意义。
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