Liu Yijie, Rong Wensheng, Zhao Xiulan, Wang Meng, Jiang Quanchun, Wang Weijian
Department of Preventive Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, China.
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Zhonghua Kou Qiang Yi Xue Za Zhi. 2014 Apr;49(4):199-203.
To evaluate the effectiveness of resin-based sealants and glass ionomer sealants on caries prevention in the first permanent molars.
A randomized controlled, examiner-blinded, 2-year clinical trial with parallel groups was conducted. A total of 419 children (664 first molars) who had at least one sound first permanent molar with deep fissures or fissures with signs of non-cavitated lesions were recruited. They were randomly allocated into three groups.Helioseal F, a light-cured resin-based sealants was used in group R (136 children with 219 first molars). FUJI VII, a light-cured glass ionomer sealants was used in group G (130 children with 218 first molars) and group N (153 children with 227 first molars) was blank control.Follow-up examinations were conducted at 6, 12, and 24 month after sealing to examine the sealants retention and caries incidence. Chi-square test was used to compare the differences of caries incidence among the 3 groups.Generalized estimating equations (GEE) was used to analyze the effective factors of caries incidence.
During the 2-year follow-up period, 3.0% (6/197) of the teeth in group R, 6.7% (13/193) of the teeth in group G, and 14.7% (29/197) of the teeth in group N were diagnosed as having developed a cavitated lesion. The difference in the incidence of caries among the three groups was significant(P < 0.05). No significant difference in caries incidence was found between group R and group G (P > 0.05). The tooth-level preventive fractions were 79.6% for resin-based sealants and 54.4% for glass ionomer sealants, respectively.
Both resin-based sealants and glass ionomer sealants can effectively prevent the incidence of caries in the first permanent molars. The two sealants have similar caries prevention effect.
评估树脂基封闭剂和玻璃离子封闭剂对第一恒磨牙防龋的有效性。
进行了一项随机对照、检查者盲法、为期2年的平行组临床试验。共招募了419名儿童（664颗第一磨牙），他们至少有一颗有深窝沟或有非龋损迹象窝沟的健康第一恒磨牙。将他们随机分为三组。R组（136名儿童，219颗第一磨牙）使用光固化树脂基封闭剂Helioseal F。G组（130名儿童，218颗第一磨牙）使用光固化玻璃离子封闭剂FUJI VII，N组（153名儿童，227颗第一磨牙）为空白对照。在封闭后6、12和24个月进行随访检查，以检查封闭剂保留情况和龋病发生率。采用卡方检验比较三组龋病发生率的差异。使用广义估计方程（GEE）分析龋病发生率的影响因素。
在2年的随访期内，R组3.0%（6/197）的牙齿、G组6.7%（13/193）的牙齿和N组14.7%（29/197）的牙齿被诊断为发生了龋损。三组龋病发生率的差异有统计学意义（P<0.05）。R组和G组之间的龋病发生率无显著差异（P>0.05）。树脂基封闭剂和玻璃离子封闭剂的牙齿水平预防率分别为79.6%和54.4%。
树脂基封闭剂和玻璃离子封闭剂均可有效预防第一恒磨牙龋病的发生。两种封闭剂的防龋效果相似。
