Zhang Li, Lin Yong, Li Jin-ke
Department of Gynecology and Obstetrics, West China Second Hospital, Sichuan University, Chengdu, Sichuan, China E-mail :
Asian Pac J Cancer Prev. 2014;15(11):4465-6. doi: 10.7314/apjcp.2014.15.11.4465.
HPV type-specific detection may promote cervical screening program and vaccination development worldwide. We conduct a study comparing HPV Hybrid capture II (HC II) Test and Hybribio GenoArray test, a newly developed HPV type-specific assay, in patients with cervical epithelial neoplasm. Results showed a good concordance in cervical HPV detection between two tests (kappa value 0.80, p<0.05, McNemar test). Our study may promote utilization of type-specific HPV detection that is helpful for cervical cancer screening and vaccination.
人乳头瘤病毒（HPV）分型检测可能会推动全球范围内的宫颈癌筛查计划和疫苗研发。我们开展了一项研究，比较了HPV杂交捕获二代（HC II）检测法与一种新开发的HPV分型检测法——Hybribio基因芯片检测法，研究对象为宫颈上皮肿瘤患者。结果显示，两种检测方法在宫颈HPV检测方面具有良好的一致性（kappa值为0.80，p<0.05，McNemar检验）。我们的研究可能会促进HPV分型检测的应用，这有助于宫颈癌筛查和疫苗接种。
