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主动脉瓣狭窄和冠状动脉疾病:我们了解多少?有哪些未知?对文献的综合回顾及提出的治疗方案。

Aortic stenosis and coronary artery disease: what do we know? What don't we know? A comprehensive review of the literature with proposed treatment algorithms.

机构信息

Columbia University Medical Center, New York, NY, USA Cardiovascular Research Foundation, New York, NY, USA Quebec Heart and Lung Institute, Quebec, Canada

Columbia University Medical Center, New York, NY, USA.

出版信息

Eur Heart J. 2014 Aug 14;35(31):2069-82. doi: 10.1093/eurheartj/ehu247. Epub 2014 Jun 26.

Abstract

Aortic valve stenosis is the most common form of valvular heart disease in the elderly population and occurs frequently in conjunction with coronary artery disease. The standard treatment option for patients with these two conditions has been surgical aortic valve replacement and coronary artery bypass grafting. The arrival of transcatheter aortic valve replacement has considerably shifted the treatment paradigms. Nevertheless, a lot of questions remain unanswered regarding the management of coronary artery disease in the setting of the transcatheter options for severe aortic stenosis. This article includes a comprehensive review of the literature and seeks to describe the actual knowledge on the topic of aortic stenosis and concomitant coronary artery disease.

摘要

主动脉瓣狭窄是老年人群中最常见的瓣膜性心脏病形式,常与冠状动脉疾病同时发生。对于这两种疾病的患者,标准的治疗选择一直是外科主动脉瓣置换和冠状动脉旁路移植术。经导管主动脉瓣置换术的出现极大地改变了治疗模式。然而,对于严重主动脉瓣狭窄的经导管治疗选择中,冠状动脉疾病的管理仍存在许多未解决的问题。本文对文献进行了全面回顾,并旨在描述主动脉瓣狭窄伴发冠状动脉疾病这一主题的现有知识。

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