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产神经毒素丁酸梭菌菌株5521的基因组序列

Genome Sequence of the Neurotoxigenic Clostridium butyricum Strain 5521.

作者信息

Hassan Karl A, Elbourne Liam D H, Tetu Sasha G, Johnson Eric A, Paulsen Ian T

机构信息

Department of Chemistry and Biomolecular Sciences, Macquarie University, NSW, Australia.

Department of Bacteriology, Botulinum Toxins Laboratory, Food Research Institute, Madison, Wisconsin, USA.

出版信息

Genome Announc. 2014 Jun 26;2(3):e00632-14. doi: 10.1128/genomeA.00632-14.

DOI:10.1128/genomeA.00632-14
PMID:24970833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4073117/
Abstract

Clostridium strains from six phylogenetic groups, C. botulinum groups I to IV, C. baratii, and C. butyricum, display the capacity to produce botulinum neurotoxin. Here, we present the genome sequence of a C. butyricum isolate, the neurotoxigenic strain 5521, which encodes the type E botulinum neurotoxin.

摘要

来自六个系统发育组的梭菌菌株，即肉毒杆菌I至IV组、巴氏梭菌和丁酸梭菌，具有产生肉毒杆菌神经毒素的能力。在此，我们展示了丁酸梭菌分离株5521的基因组序列，该菌株为产神经毒素菌株，编码E型肉毒杆菌神经毒素。

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