Sahramian Iraj, Noori Noor Mohammad, Moradi Abdolvahab, Forghani Forugh, Sharafi Elham
Department of Pediatrics, Children and Adolescent Health Research Center, Zabol University of Medical Sciences, Zabol, IR Iran.
Department of Pediatrics, Children And Adolescent Health Research Center, Zahedan University of Medical Sciences, Zahedan, IR Iran.
Int J High Risk Behav Addict. 2013 Winter;1(4):154-8. doi: 10.5812/ijhrba.7312. Epub 2013 Mar 12.
Opium abuse is one of the widespread social problems, and one of the most worrying aspects of it is the effect of parents' drug abuse on the fetus.
The present study has investigated the correlation between opium abuse during pregnancy in mothers with congenital heart defects in their children.
From early 2009 to late 2011, for two consecutive years in specialized pediatric center of Zahedan Medical University, 225 of children suffering from congenital heart defects were examined and compared with 480 healthy ones for mother opium dependency. The final data were analyzed by student t-test and χ(2) in SPSS software and the two groups were compared in terms of their parents' addiction to opium.
From 225 children under study 23.5% had addicted parents based on the variables of the study but the rate was only 2.3 for the control group. The difference between these two groups was significant and the most common form of heart disease was congenital ventricular septal defect.
Opium has teratogenic effect on cardiovascular system.
鸦片滥用是普遍存在的社会问题之一,其中最令人担忧的一个方面是父母滥用药物对胎儿的影响。
本研究调查了母亲孕期鸦片滥用与子女先天性心脏缺陷之间的相关性。
从2009年初至2011年末,在扎黑丹医科大学的专业儿科中心连续两年对225名患有先天性心脏缺陷的儿童进行了检查,并与480名健康儿童就母亲的鸦片依赖情况进行了比较。最终数据在SPSS软件中采用学生t检验和χ²检验进行分析,并就父母的鸦片成瘾情况对两组进行了比较。
在所研究的225名儿童中,根据研究变量,23.5%的儿童父母成瘾,但对照组这一比例仅为2.3%。两组之间的差异具有显著性,最常见的心脏病形式为先天性室间隔缺损。
鸦片对心血管系统有致畸作用。