使用无应激试验研究母体鸦片滥用对胎儿心率的影响。
The Effects of Maternal Opium Abuse on Fetal Heart Rate using Non-Stress Test.
作者信息
Keikha Fatemeh, Vahdani Fahimeh Ghotbizadeh, Latifi Sahar
机构信息
Department of Obstetrics and Gynecology, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Iran J Med Sci. 2016 Nov;41(6):479-485.
BACKGROUND
Opium is one of the most commonly abused opiates in developing countries including Iran. Considering the importance of maternal health on the newborn, we aimed to assess the effect of opium abuse on fetal heart rate (FHR) characteristics in a sample of pregnant women in Zahedan, Southeast Iran.
METHODS
This cross-sectional study was done on 100 pregnant women referring to Ali-Ibn-Abi Talib Hospital in Zahedan, during 2011-2013. The participants were divided into two groups comprising of opium abusers and healthy individuals. The participants received 500cc intravenous fluid containing dextrose and then non-stress test results were recorded for 20 minutes.
RESULTS
We found no significant difference between the two groups with respect to their demographic characteristics. Fetal movements, variability, acceleration, and reactivity were significantly higher among addicted women (P<0.0001 for all). Periodic change was 9.8 times higher among opium abusers compared with the healthy women. Abnormal variability or oscillations of <15 beats/min, which indicates lack of beat-to-beat variability, was significantly higher in the fetuses of addicted mothers (P<0.0001).
CONCLUSION
Considering significant abnormal patterns in FHR characteristics among the opium abuser group, mothers addicted to opium need specific prenatal care.
背景
在包括伊朗在内的发展中国家，鸦片是最常被滥用的阿片类药物之一。鉴于孕产妇健康对新生儿的重要性，我们旨在评估伊朗东南部扎黑丹的一组孕妇中鸦片滥用对胎儿心率（FHR）特征的影响。
方法
这项横断面研究于2011年至2013年期间对转诊至扎黑丹阿里 - 伊本 - 阿比·塔利卜医院的100名孕妇进行。参与者被分为两组，即鸦片滥用者组和健康个体组。参与者接受含有葡萄糖的500cc静脉输液，然后记录20分钟的无应激试验结果。
结果
我们发现两组在人口统计学特征方面没有显著差异。成瘾女性的胎儿运动、变异性、加速和反应性显著更高（所有P<0.0001）。鸦片滥用者的周期性变化是健康女性的9.8倍。成瘾母亲胎儿中异常变异性或每分钟<15次心跳的振荡（表明缺乏逐搏变异性）显著更高（P<0.0001）。
结论
考虑到鸦片滥用者组胎儿心率特征存在显著异常模式，成瘾母亲需要特殊的产前护理。
Zotero 插件