Spaniol Kristina, Stupp Tobias, Melcher Carola, Beheiri Nadja, Eter Nicole, Prokosch Verena
University Eye Hospital Düsseldorf, Düsseldorf, Germany.
University Eye Hospital Münster, Münster, Germany.
Am J Perinatol. 2015 Feb;32(3):271-6. doi: 10.1055/s-0034-1383847. Epub 2014 Jun 27.
Congenital nasolacrimal duct obstruction (CNDO) is the most common cause of neonatal epiphora. Persistence can lead to chronic dacryocystitis and amblyopia. This study analyzed the association between the incidence of CNDO and delivery by cesarean section.
This was a retrospective cohort study of 386 children with CNDO (born between 2000 and 2008). The incidence of the delivery mode in patients with CNDO was compared with data from a corresponding population derived from annual birth statistics.
There was no statistically significant association between the overall cesarean section rate and the incidence of CNDO, but primary cesarean section was significantly more frequent among patients with CNDO (73.15%, p < 0.05). The difference was significant for both genders for the period from 2000 to 2008 (p < 0.05%). The relative risk for CNDO was 1.7-fold increased in children delivered by primary cesarean section.
Primary cesarean section may be a risk factor for CNDO.
先天性鼻泪管阻塞（CNDO）是新生儿泪溢最常见的原因。病情持续可能导致慢性泪囊炎和弱视。本研究分析了CNDO发病率与剖宫产之间的关联。
这是一项对386例CNDO患儿（2000年至2008年出生）的回顾性队列研究。将CNDO患者的分娩方式发生率与来自年度出生统计数据的相应人群的数据进行比较。
总体剖宫产率与CNDO发病率之间无统计学显著关联，但CNDO患者中初次剖宫产明显更为常见（73.15%，p < 0.05）。2000年至2008年期间，男女两性的差异均显著（p < 0.05%）。初次剖宫产分娩的儿童患CNDO的相对风险增加了1.7倍。
初次剖宫产可能是CNDO的一个风险因素。
