Kuhli-Hattenbach Claudia, Lüchtenberg M, Hofmann C, Kohnen T
Klinik für Augenheilkunde, Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.
Klinik für Kinderaugenheilkunde, Schielbehandlung und plastisch-rekonstruktive Lidchirurgie, Bürgerhospital, Frankfurt am Main, Deutschland.
Ophthalmologe. 2016 Aug;113(8):675-83. doi: 10.1007/s00347-016-0230-z.
Congenital nasolacrimal duct obstruction (dacryostenosis) with a persisting membrane at Hasner's valve is the most common cause of persistent tear and ocular discharge in infants.
To evaluate whether there is an association between congenital dacryostenosis and delivery via cesarean section.
In a prospective study we examined 107 children (mean age 9.2 ± 7.1 months) with congenital dacryostenosis. We evaluated data about the mode of delivery (vaginal delivery versus cesarean section) and gestational age at the time of birth. Within the first 8 months of life children were treated by probing using local anesthesia, whereas older children were treated using general anesthesia. After the age of 11 months treatment included nasolacrimal duct intubation with a bicanalicular stent. Statistical analyses were performed using binomial tests, Fisher's exact test and the t-test.
In this study 51 children delivered by cesarean section were compared with 56 children delivered by spontaneous vaginal delivery. A total of 44 age-matched pairs from both groups were evaluated in order to eliminate confounding factors due to gestational age at delivery. Based on the published rate of cesarean sections from the same region of the State of Hesse between 2002-2004 we observed a statistically significant association between congenital dacryostenosis and delivery by cesarean section among the 88 age-matched patients (P = 0.009). Moreover, subgroup analysis revealed a significant association between congenital dacryostenosis and delivery by primary cesarean section (P = 0.00004). The prevalence of surgical treatment was not statistically different between both groups based on the mode of delivery (P = 0.8).
Our results suggest that delivery via cesarean section is associated with a significantly higher prevalence of congenital dacryostenosis.
先天性鼻泪管阻塞(泪道狭窄)伴哈氏瓣膜处膜状物持续存在是婴儿持续性流泪和眼部分泌物增多的最常见原因。
评估先天性泪道狭窄与剖宫产分娩之间是否存在关联。
在一项前瞻性研究中,我们检查了107例先天性泪道狭窄患儿(平均年龄9.2±7.1个月)。我们评估了分娩方式(阴道分娩与剖宫产)以及出生时的孕周数据。出生后8个月内的患儿采用局部麻醉下的探通术治疗,而年龄较大的患儿则采用全身麻醉治疗。11个月龄后,治疗包括使用双泪小管支架进行鼻泪管插管。采用二项检验、Fisher精确检验和t检验进行统计分析。
本研究中,51例剖宫产分娩的患儿与56例自然阴道分娩的患儿进行了比较。为消除分娩时孕周导致的混杂因素,对两组中总共44对年龄匹配的患儿进行了评估。根据黑森州同一地区2002 - 2004年公布的剖宫产率,我们观察到在88例年龄匹配的患者中,先天性泪道狭窄与剖宫产分娩之间存在统计学上的显著关联(P = 0.009)。此外,亚组分析显示先天性泪道狭窄与首次剖宫产分娩之间存在显著关联(P = 0.00004)。基于分娩方式,两组手术治疗的患病率在统计学上无差异(P = 0.8)。
我们的结果表明,剖宫产分娩与先天性泪道狭窄的患病率显著升高有关。