Lafarga Tomas, Hayes Maria
Teagasc, The Irish Agricultural and Food Development Authority, Food BioSciences Department, Ashtown, Dublin 15, Dublin, Republic of Ireland.
Teagasc, The Irish Agricultural and Food Development Authority, Food BioSciences Department, Ashtown, Dublin 15, Dublin, Republic of Ireland.
Meat Sci. 2014 Oct;98(2):227-39. doi: 10.1016/j.meatsci.2014.05.036. Epub 2014 Jun 8.
Bioactive peptides are sequences of between 2-30 amino acids in length that impart a positive health effect to the consumer when ingested. They have been identified from a range of foods, including milk and muscle sources including beef, chicken, pork and marine muscles. The myriad of peptides identified from these sources have known antihypertensive, opioid, antioxidant, antithrombotic and other bioactivities. Indeed, bioactive peptides could play a role in the prevention of diseases associated with the development of metabolic syndrome and mental health diseases. The aim of this work is to present an overview of the bioactive peptides identified in muscle proteins and by-products generated during the processing of meat. The paper looks at the isolation, enrichment and characterisation strategies that have been employed to date to generate bioactive peptides and the potential future applications of these peptides in functional foods for the prevention of heart and mental health problems and obesity.
生物活性肽是长度在2至30个氨基酸之间的序列,摄入后会给消费者带来积极的健康影响。它们已从一系列食物中被鉴定出来,包括牛奶以及肌肉来源,如牛肉、鸡肉、猪肉和海洋肌肉。从这些来源中鉴定出的大量肽具有已知的抗高血压、类阿片、抗氧化、抗血栓形成和其他生物活性。事实上,生物活性肽可能在预防与代谢综合征和精神健康疾病发展相关的疾病中发挥作用。这项工作的目的是概述在肌肉蛋白以及肉类加工过程中产生的副产品中鉴定出的生物活性肽。本文探讨了迄今为止用于生成生物活性肽的分离、富集和表征策略,以及这些肽在预防心脏和精神健康问题及肥胖的功能性食品中的潜在未来应用。