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小脑下外侧脚入路治疗延髓背外侧海绵状血管畸形

Lateral inferior cerebellar peduncle approach to dorsolateral medullary cavernous malformation.

作者信息

Deshmukh Vivek R, Rangel-Castilla Leonardo, Spetzler Robert F

机构信息

Department of Neurosurgery, Providence Brain and Spine Institute, Portland, Oregon; and.

出版信息

J Neurosurg. 2014 Sep;121(3):723-9. doi: 10.3171/2014.5.JNS132276. Epub 2014 Jun 27.

Abstract

OBJECT

Brainstem cavernous malformations (BSCMs) present a unique therapeutic challenge to neurosurgeons. Resection of BSCMs is typically reserved for lesions that reach pial or ependymal surfaces. The current study investigates the lateral inferior cerebellar peduncle as a corridor to dorsolateral medullary BSCMs.

METHODS

In this retrospective review, the authors present the cases of 4 patients (3 women and 1 man) who had a symptomatic dorsolateral cavernous malformation with radiographic and clinical evidence of hemorrhage.

RESULTS

All patients underwent excision of the cavernous malformation via a far-lateral suboccipital craniotomy through the foramen of Luschka and with an incision in the inferior cerebellar peduncle. On intraoperative examination, 2 of the 4 patients had hemosiderin staining on the surface of the peduncle. All lesions were completely excised and all patients had a good or excellent outcome (modified Rankin Scale scores of 0 or 1).

CONCLUSIONS

This case series illustrates that intrinsic lesions of the dorsolateral medulla can be safely removed laterally through the foramen of Luschka and the inferior cerebellar peduncle.

摘要

目的

脑干海绵状血管畸形(BSCMs)给神经外科医生带来了独特的治疗挑战。BSCMs的切除通常适用于累及软脑膜或室管膜表面的病变。本研究探讨将小脑下外侧脚作为通向延髓背外侧BSCMs的通道。

方法

在这项回顾性研究中,作者介绍了4例患者(3名女性和1名男性)的病例,这些患者患有有症状的延髓背外侧海绵状血管畸形,并有影像学和临床出血证据。

结果

所有患者均通过经Luschka孔的远外侧枕下开颅术并切开小脑下脚进行海绵状血管畸形切除。术中检查发现,4例患者中有2例在小脑下脚表面有含铁血黄素染色。所有病变均被完全切除,所有患者预后良好或极佳(改良Rankin量表评分为0或1)。

结论

该病例系列表明,延髓背外侧的内在病变可通过Luschka孔和小脑下脚从外侧安全切除。

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