Miyagawa Mai, Maeda Masayuki, Umino Maki, Kagawa Ken, Nakamichi Kazuo, Sakuma Hajime, Tomimoto Hidekazu
Department of Radiology, Mie University School of Medicine, Japan.
Department of Radiology, Mie University School of Medicine, Japan.
J Neurol Sci. 2014 Sep 15;344(1-2):198-202. doi: 10.1016/j.jns.2014.06.018. Epub 2014 Jun 19.
Magnetic resonance imaging (MRI) is a useful tool for diagnosing and monitoring progressive multifocal leukoencephalopathy (PML). Although characteristic MRI findings of PML are well known, we noted a potential new finding for this disease on susceptibility-weighted imaging (SWI). Two patients with PML were studied and followed using MRI. SWI revealed low signal intensities in U-fibers adjacent to the white matter lesions of PML. These findings progressed along with the disease progression. The cause underlying these findings remains unclear. This new finding suggests that SWI is useful for the diagnosis of PML. It can provide a helpful clue in a clinical setting.
磁共振成像（MRI）是诊断和监测进行性多灶性白质脑病（PML）的一种有用工具。尽管PML的典型MRI表现广为人知，但我们在磁敏感加权成像（SWI）上发现了该病一个潜在的新表现。对两名PML患者进行了MRI研究及随访。SWI显示PML白质病变附近的U形纤维呈低信号强度。这些表现随着疾病进展而变化。这些表现背后的原因尚不清楚。这一新发现提示SWI对PML的诊断有用。它能在临床环境中提供有用线索。
