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洗衣店毛巾中重金属残留风险的定量评估及其对工人的影响

A quantitative assessment of risks of heavy metal residues in laundered shop towels and their use by workers.

作者信息

Connor Kevin, Magee Brian

机构信息

ARCADIS U.S., Inc., One Executive Drive, Suite 303, Chelmsford, MA 01824, USA.

ARCADIS U.S., Inc., One Executive Drive, Suite 303, Chelmsford, MA 01824, USA.

出版信息

Regul Toxicol Pharmacol. 2014 Oct;70(1):125-37. doi: 10.1016/j.yrtph.2014.06.020. Epub 2014 Jun 26.

Abstract

This paper presents a risk assessment of exposure to metal residues in laundered shop towels by workers. The concentrations of 27 metals measured in a synthetic sweat leachate were used to estimate the releasable quantity of metals which could be transferred to workers' skin. Worker exposure was evaluated quantitatively with an exposure model that focused on towel-to-hand transfer and subsequent hand-to-food or -mouth transfers. The exposure model was based on conservative, but reasonable assumptions regarding towel use and default exposure factor values from the published literature or regulatory guidance. Transfer coefficients were derived from studies representative of the exposures to towel users. Contact frequencies were based on assumed high-end use of shop towels, but constrained by a theoretical maximum dermal loading. The risk estimates for workers developed for all metals were below applicable regulatory risk benchmarks. The risk assessment for lead utilized the Adult Lead Model and concluded that predicted lead intakes do not constitute a significant health hazard based on potential worker exposures. Uncertainties are discussed in relation to the overall confidence in the exposure estimates developed for each exposure pathway and the likelihood that the exposure model is under- or overestimating worker exposures and risk.

摘要

本文介绍了工人接触洗衣店毛巾中金属残留的风险评估。合成汗液浸出液中测得的27种金属浓度用于估算可转移至工人皮肤的金属释放量。采用一个关注毛巾到手以及随后手到食物或口部转移的暴露模型对工人暴露情况进行定量评估。该暴露模型基于关于毛巾使用的保守但合理的假设以及已发表文献或监管指南中的默认暴露因子值。转移系数源自针对毛巾使用者暴露情况的代表性研究。接触频率基于假定的洗衣店毛巾高端使用情况,但受理论最大皮肤负荷限制。为所有金属得出的工人风险估计值均低于适用的监管风险基准。铅的风险评估采用了成人铅模型,并得出结论,基于潜在的工人暴露情况,预测的铅摄入量不构成重大健康危害。文中讨论了与为每种暴露途径得出的暴露估计值的总体置信度以及暴露模型低估或高估工人暴露和风险的可能性相关的不确定性。

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