Merkus Suzanne L, Holte Kari Anne, Huysmans Maaike A, Hansen Åse Marie, van de Ven Peter M, van Mechelen Willem, van der Beek Allard J
Research Group Work and Safety, International Research Institute of Stavanger, P. O. Box 8046, 4068, Stavanger, Norway.
Int Arch Occup Environ Health. 2015 Feb;88(2):247-57. doi: 10.1007/s00420-014-0954-5. Epub 2014 Jun 29.
The study aimed to investigate the course and duration of neuroendocrine recovery after 2-week 12-h day and night shift working periods and to study whether there were differences in recovery between the shift groups.
Twenty-nine male offshore employees working 2-week 12-h shift tours participated in the study; 15 participated after a day shift tour and 14 after a night shift tour. Salivary cortisol was assessed at awakening, 30 min after awakening, and before bedtime on the 1st, 4th, 7th, and 11th day of the free period, with a reference day prior to the offshore tour. Differences were tested using generalised estimating equations analysis.
Compared to the reference day, night shift workers had a significantly flatter cortisol profile on the 1st day off, significantly lower cortisol concentrations at 30 min after awakening on day 4 and at awakening on day 7, and a significantly smaller decline to evening concentration on days 4 and 11. Compared to the reference day, day shift workers only showed a significantly lower cortisol concentration at awakening on the 1st day off. Compared to day workers, night shift workers had a flatter profile on the 1st day off and a lower cortisol concentration at awakening on the 4th day.
Following 2-week 12-h night shift working periods, recovery was not fully complete up to day 11. Following 2-week 12-h day shift working periods, an indication of incomplete recovery was found on the 1st day off, with full recovery reached on day 4.
本研究旨在调查为期2周、每天工作12小时的昼夜轮班工作后神经内分泌恢复的过程和持续时间，并研究不同轮班组之间的恢复情况是否存在差异。
29名从事为期2周、每天12小时轮班工作的男性海上员工参与了本研究；其中15人在白班轮班后参与，14人在夜班轮班后参与。在休息期的第1天、第4天、第7天和第11天，以及海上工作期前的一个参考日，分别于醒来时、醒来后30分钟和就寝前评估唾液皮质醇水平。使用广义估计方程分析来检验差异。
与参考日相比，夜班工作者在休息第1天的皮质醇水平曲线明显更平缓，在第4天醒来后30分钟和第7天醒来时的皮质醇浓度显著更低，在第4天和第11天晚上皮质醇浓度的下降幅度显著更小。与参考日相比，白班工作者仅在休息第1天醒来时的皮质醇浓度显著更低。与日班工作者相比，夜班工作者在休息第1天的水平曲线更平缓，在第4天醒来时的皮质醇浓度更低。
在为期2周、每天12小时的夜班工作后，直到第11天恢复仍未完全完成。在为期2周、每天12小时的白班工作后，在休息第1天发现恢复不完全的迹象，在第4天完全恢复。
