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利比亚乙型和丙型肝炎病毒感染及其相关危险因素的流行情况:一项全国血清流行病学调查。

Prevalence of hepatitis B and C virus infections and their related risk factors in Libya: a national seroepidemiological survey.

出版信息

East Mediterr Health J. 2013 Jul;19(7):589-99.

PMID:24975303
Abstract

A high prevalence of hepatitis B (HBV) and C virus (HCV) infections has been reported among specific patient groups in Libya; a survey was thus designed to determine the extent of the problem at the national level. A multi-stage sampling design covering all administrative areas of Libya was applied, covering > 65,000 individuals of all age groups. All subjects gave a blood sample and completed a questionnaire on demographic and risk behaviour data. The prevalence of HBV surface antigen (HBsAg) and anti-HCV were 2.2% and 1.3% respectively. The prevalence of anti-HCV increased with age, rising gradually after age 30 years, in contrast to a stable prevalence of HBsAg in all age groups 10+ years. Age-adjusted risk factors for HCV infection were previous hospitalization, surgical operations, previous blood transfusions and intravenous drug use; for HBV infection only family exposure or contact with HBV case were identified.

摘要

在利比亚的特定患者群体中,乙型肝炎(HBV)和丙型肝炎(HCV)病毒感染的患病率很高;因此,设计了一项调查,以确定全国范围内的问题程度。采用多阶段抽样设计覆盖利比亚的所有行政区,涵盖了 > 65000 名所有年龄组的个体。所有受试者均采集血样并填写了一份关于人口统计学和风险行为数据的问卷。HBV 表面抗原(HBsAg)和抗-HCV 的流行率分别为 2.2%和 1.3%。抗-HCV 的流行率随年龄增长而增加,在 30 岁后逐渐上升,而 HBsAg 在所有年龄组中 10 岁以上的流行率保持稳定。调整年龄因素后,HCV 感染的危险因素为既往住院、手术、既往输血和静脉吸毒;HBV 感染仅确定了家庭接触或与 HBV 病例接触。

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