Tardani Franco, La Mesa Camillo
Department of Chemistry, Sapienza University of Rome, Piazzale A. Moro, 5, I-00185 Rome, Italy.
Department of Chemistry, Sapienza University of Rome, Piazzale A. Moro, 5, I-00185 Rome, Italy.
Colloids Surf B Biointerfaces. 2014 Sep 1;121:165-70. doi: 10.1016/j.colsurfb.2014.06.004. Epub 2014 Jun 7.
The possibility to disperse carbon nanotubes in biocompatible matrices has got substantial interest from the scientific community. Along this research line, the inclusion of single walled carbon nanotubes in lysozyme-based hydrogels was investigated. Experiments were performed at different nanotube/lysozyme weight ratios. Carbon nanotubes were dispersed in protein solutions, in conditions suitable for thermal gelation. The state of the dispersions was determined before and after thermal treatment. Rheology, dynamic light scattering and different microscopies investigated the effect that carbon nanotubes exert on gelation. The gelation kinetics and changes in gelation temperature were determined. The effect of carbon and lysozyme content on the gel properties was, therefore, determined. At fixed lysozyme content, moderate amounts of carbon nanotubes do not disturb the properties of hydrogel composites. At moderately high volume fractions in carbon nanotubes, the gels become continuous in both lysozyme and nanotubes. This is because percolating networks are presumably formed. Support to the above statements comes by rheology.
将碳纳米管分散在生物相容性基质中的可能性引起了科学界的广泛关注。沿着这条研究路线，研究了将单壁碳纳米管纳入基于溶菌酶的水凝胶中。实验在不同的纳米管/溶菌酶重量比下进行。碳纳米管在适合热凝胶化的条件下分散在蛋白质溶液中。在热处理前后测定分散体的状态。流变学、动态光散射和不同的显微镜技术研究了碳纳米管对凝胶化的影响。测定了凝胶化动力学和凝胶化温度的变化。因此，确定了碳和溶菌酶含量对凝胶性质的影响。在溶菌酶含量固定的情况下，适量的碳纳米管不会干扰水凝胶复合材料的性质。在碳纳米管的体积分数适中较高时，凝胶在溶菌酶和纳米管中都变得连续。这可能是因为形成了渗流网络。流变学为上述说法提供了支持。
