Dam Lyanne, in 't Hof Klaas H, Smit Natalie, Nieveen van Dijkum Els J M
Maastricht Universitair Medisch Centrum, afd. Keel-, Neus- en Oorheelkunde, Maastricht: drs. L. Dam, aios kno.
Ned Tijdschr Geneeskd. 2014;158:A7287.
Multinodular goitre has a slow and progressive growth. The clinical presentation of patients with multinodular goitre is variable and dependent on size, location and the functional state of the thyroid tissue. The most frequent clinical symptoms are caused by compression and deviation of the trachea and range from dyspnoea to acute asphyxia. Imaging is important to confirm the size of the multinodular goitre. Timing of the treatment can be critical. However, a good treatment guideline is lacking. There are two treatment options: radioactive iodine and surgical resection. The best treatment option and timing of treatment for patients with multinodular goitre should be assessed and decided on an individual basis. In this clinical report we present two patients who had a multinodular goitre with progressive symptoms for years. Patient A, 66 years of age, was successfully treated with radioactive iodine. Patient B, 77 years of age, underwent a total thyroidectomy.
结节性甲状腺肿生长缓慢且呈进行性。结节性甲状腺肿患者的临床表现各异，取决于甲状腺组织的大小、位置及功能状态。最常见的临床症状由气管受压和移位引起，范围从呼吸困难到急性窒息。影像学检查对于确定结节性甲状腺肿的大小很重要。治疗时机可能至关重要。然而，目前缺乏完善的治疗指南。有两种治疗选择：放射性碘和手术切除。对于结节性甲状腺肿患者，最佳治疗方案和治疗时机应根据个体情况进行评估和决定。在本临床报告中，我们介绍了两名患有结节性甲状腺肿且多年来症状逐渐加重的患者。患者A，66岁，成功接受放射性碘治疗。患者B，77岁，接受了全甲状腺切除术。
