Lutze G, Canzler E, Presser H J
Institut für Klinische Chemie und Laboratoriumsdiagnostik, Medizinischen Akademie Magdeburg.
Zentralbl Gynakol. 1989;111(3):167-72.
Pathologic inhibitors of blood coagulation as cause of acquired haemostatic failure are rare. We report about a 23 years old primigravida with a life-threatening haemorrhage post partum. Analysis of coagulation parameters showed the presence of inhibitor to factor VIII. We reacted successfully with cyclophosphamid and cryoprecipitated factor VIII. References to diagnostic and therapy of pathologic clotting factor inhibitors are described.
作为获得性止血功能衰竭病因的病理性凝血抑制剂很罕见。我们报告了一名23岁初产妇，产后发生危及生命的出血。凝血参数分析显示存在抗凝血因子VIII抑制剂。我们用环磷酰胺和冷沉淀凝血因子VIII成功治疗。文中描述了病理性凝血因子抑制剂的诊断和治疗。
