急性冠状动脉综合征与种族：来自中东地区的观察结果
Acute coronary syndrome and ethnicity: observations from the Middle East.
作者信息
Ahmed Emad, Gehani Aa, El-Menyar Ayman, AlBinAli Hajar A, Singh Rajvir, Al Suwaidi Jassim
机构信息
Department of Adult Cardiology & Cardiovascular Surgery, Heart Hospital, Hamad Medical Corporation (HMC), Doha, Qatar.
出版信息
Future Cardiol. 2014 May;10(3):337-48. doi: 10.2217/fca.14.10.
AIMS
To evaluate the presentation and outcome of South Asian (SAP) to Middle Eastern Arabs (MEAP) patients presenting with acute coronary syndrome.
METHODS
Data were collected retrospectively in Qatar between 1991 and 2010, and were analyzed according to patient ethnicity.
RESULTS
Of 14,593 acute coronary syndrome patients, 49% were MEAP and 51% were SAP. When compared with MEAP, SAP were younger, males and smokers (p < 0.01). Other cardiovascular risk factors were less common in SAP when compared with MEAP. ST-elevation myocardial infarction and the use of evidence-based medications were more prevalent among SAP (all p < 0.001). Compared to MEAP, SAP had better in-hospital outcomes; however, ethnicity was not an independent predictor of in-hospital mortality.
CONCLUSION
In contrary to data from Western countries, SAP living in the Middle East are younger with lower cardiovascular risk profile and better outcomes when compared with Arab patients. However, further studies are warranted.
目的
评估患有急性冠状动脉综合征的南亚（SAP）和中东阿拉伯（MEAP）患者的临床表现及预后。
方法
回顾性收集1991年至2010年卡塔尔的数据，并根据患者种族进行分析。
结果
在14593例急性冠状动脉综合征患者中，49%为MEAP患者，51%为SAP患者。与MEAP患者相比，SAP患者更年轻，男性居多且吸烟（p<0.01）。与MEAP患者相比，SAP患者的其他心血管危险因素较少见。ST段抬高型心肌梗死和循证药物的使用在SAP患者中更为普遍（均p<0.001）。与MEAP患者相比，SAP患者的院内结局更好；然而，种族并非院内死亡率的独立预测因素。
结论
与西方国家的数据相反，居住在中东的SAP患者比阿拉伯患者更年轻，心血管风险状况更低，预后更好。然而，仍需进一步研究。
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