Dubai Heart Centre, Dubai Health Authority, United Arab Emirates.
Angiology. 2011 Jul;62(5):390-6. doi: 10.1177/0003319710387921. Epub 2011 Feb 8.
Our objective was to validate the Global Registry of Acute Coronary Events (GRACE) risk score for in-hospital mortality in a Middle Eastern acute coronary syndrome (ACS) population enrolled in the Gulf Registry of Acute Coronary Events (Gulf RACE). Out of 8176, unselected, consecutive patients with ACS, during 6 months in 2006 and 2007 from 63 hospitals in 6 Arab countries in the Middle East Gulf region, 7709 (94.3%) with available data were included. The main outcome measures were discriminatory performance (using C-index) and calibration of the GRACE risk score (in-hospital mortality predicted by GRACE risk score versus the actual mortality). In-hospital mortality in the Gulf RACE was 3.09% (n = 238). The discriminatory performance of the GRACE risk scores in the Gulf RACE was good overall (C-index = 0.86). Observed and predicted risk corresponded well in each stratum of risk of in-hospital mortality. This suggests its suitability for clinical use in this patient population.
我们的目标是验证全球急性冠状动脉事件注册（GRACE）风险评分在中东急性冠状动脉综合征（ACS）人群中的院内死亡率的有效性，该人群纳入了海湾急性冠状动脉事件注册（Gulf RACE）。在 2006 年和 2007 年的 6 个月期间，从中东海湾地区的 6 个阿拉伯国家的 63 家医院中，选择了 8176 例未选择的连续 ACS 患者，其中 7709 例（94.3%）具有可用数据。主要观察指标为 GRACE 风险评分的判别性能（使用 C 指数）和校准（GRACE 风险评分预测的院内死亡率与实际死亡率）。Gulf RACE 的院内死亡率为 3.09%（n=238）。总体而言，GRACE 风险评分在 Gulf RACE 中的判别性能良好（C 指数=0.86）。在每个院内死亡率风险分层中，观察到的风险和预测的风险都非常吻合。这表明其适合在该患者人群中进行临床应用。
