牛血清白蛋白和人胰岛素纤维化过程中在气-水界面的落射荧光成像。
epi-Fluorescence imaging at the air-water interface of fibrillization of bovine serum albumin and human insulin.
作者信息
Sessions Kristen, Sacks Stuart, Li Shanghao, Leblanc Roger M
机构信息
Department of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33146, USA.
出版信息
Chem Commun (Camb). 2014 Aug 18;50(64):8955-7. doi: 10.1039/c4cc04030a.
PMID:24976597
Abstract
Protein fibrillization is associated with many devastating neurodegenerative diseases. This process has been studied using spectroscopic and microscopic methods. In this study, epi-fluorescence at the air-water interface was developed as an innovative technique for observing fibrillization of bovine serum albumin and human insulin.
摘要
蛋白质纤维化与许多毁灭性的神经退行性疾病相关。人们已使用光谱学和显微镜方法对这一过程展开研究。在本研究中，空气-水界面处的落射荧光被开发为一种用于观察牛血清白蛋白和人胰岛素纤维化的创新技术。
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