Bonvicino Cibele R, Moreira Miguel A, Soares Marcelo A
Cibele R Bonvicino, Miguel A Moreira, Marcelo A Soares, Genetics Division, Instituto Nacional de Câncer, Rio de Janeiro, RJ 20231-050, Brazil.
World J Gastroenterol. 2014 Jun 28;20(24):7665-74. doi: 10.3748/wjg.v20.i24.7665.
The hepatitis B virus (HBV) is a cosmopolitan infectious agent currently affecting over 350 million people worldwide, presently accounting for more than two billion infections. In addition to man, other hepatitis virus strains infect species of several mammalian families of the Primates, Rodentia and Chiroptera orders, in addition to birds. The mounting evidence of HBV infection in African, Asian and neotropical primates draws attention to the potential cross-species, zoonotic transmission of these viruses to man. Moreover, recent evidence also suggests the humans may also function as a source of viral infection to other mammals, particularly to domestic animals like poultry and swine. In this review, we list all evidence of HBV and HBV-like infection of nonhuman mammals and discuss their potential roles as donors or recipients of these viruses to humans and to other closely-related species.
乙型肝炎病毒（HBV）是一种全球性感染因子，目前全球有超过3.5亿人受其影响，总计感染人数超过20亿。除人类外，其他肝炎病毒株还感染灵长目、啮齿目和翼手目几个哺乳动物科的物种以及鸟类。在非洲、亚洲和新热带灵长类动物中，越来越多的证据表明HBV感染，这引起了人们对这些病毒跨物种、人畜共患传播给人类的潜在关注。此外，最近的证据还表明，人类也可能成为其他哺乳动物，特别是家禽和猪等家畜的病毒感染源。在这篇综述中，我们列出了所有非人类哺乳动物感染HBV和类HBV的证据，并讨论了它们作为这些病毒的供体或受体对人类和其他密切相关物种的潜在作用。
