Benore Ethan, D'Auria Alexandra, Banez Gerard A, Worley Sarah, Tang Anne
*Children's Hospital, Cleveland Clinic, Cleveland †Department of Psychology, Kent State University, Kent, OH.
Clin J Pain. 2015 May;31(5):375-83. doi: 10.1097/AJP.0000000000000127.
This study investigates the relationship between anxiety reduction and functional outcomes in children and adolescents receiving intensive interdisciplinary rehabilitation services for chronic pain (CP). Specifically, we evaluated whether: (1) anxiety changes over the course of treatment; (2) anxiety covaries with functional outcomes to rehabilitation; and (3) change in anxiety predicts change in functional outcomes from rehabilitation for CP. Using 3 separate measures assessing anxiety-related constructs, we hypothesized that anxiety would be associated with functioning, both before and following intensive rehabilitation for CP. Further, we hypothesized that a decrease in anxiety-related symptoms following rehabilitation would predict a positive change in functional outcomes.
Our sample consisted of 119 children and adolescents treated for CP in an interdisciplinary rehabilitation program between 2007 and 2012. Children completed 3 measures related to anxiety (general anxiety, pain-specific anxiety, pain catastrophizing) and 2 functional outcome measures (eg, Bath Adolescent Pain Questionnaire, PedsQL) as part of clinical care.
Measures of anxiety-related constructs were significantly correlated with measures of impairment and functioning, both at admission and at 1-month postdischarge. Regression analyses demonstrated that, after controlling for age, sex, and pain level at admission, a decrease in anxiety significantly predicted between 14% and 40% unique variance in functional outcomes.
The findings of this study support existing research on anxiety and CP, specifically the relationship between anxiety and pain-related disability. This study also supports the benefit of intensive interdisciplinary rehabilitation for both reducing anxiety and increasing functional outcomes, suggesting a possible link in children's response to intervention. Study limitations and future directions for related research are discussed.
本研究调查了接受慢性疼痛(CP)强化跨学科康复服务的儿童和青少年焦虑减轻与功能结果之间的关系。具体而言,我们评估了:(1)焦虑在治疗过程中是否发生变化;(2)焦虑与康复功能结果是否共变;以及(3)焦虑的变化是否能预测CP康复功能结果的变化。我们使用3种单独的测量方法评估与焦虑相关的构念,假设在CP强化康复前后,焦虑都与功能有关。此外,我们假设康复后焦虑相关症状的减轻将预示功能结果的积极变化。
我们的样本包括2007年至2012年间在一个跨学科康复项目中接受CP治疗的119名儿童和青少年。作为临床护理的一部分,儿童完成了3项与焦虑相关的测量(一般焦虑、疼痛特异性焦虑、疼痛灾难化)和2项功能结果测量(例如,巴斯青少年疼痛问卷、儿童生活质量量表)。
在入院时和出院后1个月,与焦虑相关构念的测量与损伤和功能测量显著相关。回归分析表明,在控制了年龄、性别和入院时的疼痛水平后,焦虑的降低显著预测了功能结果中14%至40%的独特方差。
本研究结果支持了关于焦虑与CP的现有研究,特别是焦虑与疼痛相关残疾之间的关系。本研究还支持了强化跨学科康复在减轻焦虑和改善功能结果方面的益处,表明儿童对干预的反应可能存在联系。讨论了研究局限性和相关研究的未来方向。