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65岁及以上女性良性疾病的腹腔镜与经阴道子宫切除术:倾向评分匹配分析

Laparoscopic versus vaginal hysterectomy for benign indications in women aged 65 years or older: propensity-matched analysis.

作者信息

Bogani Giorgio, Cromi Antonella, Uccella Stefano, Serati Maurizio, Casarin Jvan, Pinelli Ciro, Lazzarini Chiara, Ghezzi Fabio

机构信息

From the Department of Obstetrics and Gynecology, University of Insubria, Del Ponte Hospital, Varese, Italy.

出版信息

Menopause. 2015 Jan;22(1):32-5. doi: 10.1097/GME.0000000000000263.

Abstract

OBJECTIVE

The present study aimed to evaluate surgical operation-related outcomes of laparoscopic hysterectomy (LH) and vaginal hysterectomy (VH) for the treatment of benign uterine diseases, other than pelvic organ prolapse, in women aged 65 years or older.

METHODS

Data of women who underwent LH and VH between 2000 and 2013 were compared using propensity-matched analysis. Postoperative complications were graded according to the Accordion Severity Grading. Martin criteria were applied to improve the quality of complications reporting.

RESULTS

The study group included 40 propensity-matched participant pairs (80 women) who underwent VH and LH. No significant differences in baseline characteristics were observed between groups. A trend toward longer median operative time was observed in the LH group, in comparison with the VH group (75 [range, 20-340] vs 60 [range, 30-140] min; P = 0.09), whereas LH correlated with shorter hospital stay and lower blood loss in comparison with VH (P < 0.05). One intraoperative complication occurred during VH (bladder injury); no intraoperative complications were recorded in the LH group. No differences in Accordion grade 2 (or worse) postoperative complications were observed (1 of 40 [2.5%] in the LH group vs 3 of 40 [7.5%] in the VH group; P = 0.61; odds ratio, 3.1; 95% CI, 0.3-31.8), and no postoperative deaths occurred.

CONCLUSIONS

Our findings suggest the noninferiority of LH to VH. LH improves the postoperative course of older women undergoing surgical operation for benign uterine diseases. If an appropriate indication exists, LH should not be denied based on mere chronological age.

摘要

目的

本研究旨在评估65岁及以上女性腹腔镜子宫切除术(LH)和经阴道子宫切除术(VH)治疗除盆腔器官脱垂外的良性子宫疾病的手术相关结局。

方法

采用倾向评分匹配分析比较2000年至2013年间接受LH和VH手术的女性数据。术后并发症根据手风琴严重程度分级进行分级。应用马丁标准以提高并发症报告的质量。

结果

研究组包括40对倾向评分匹配的参与者(80名女性),她们接受了VH和LH手术。两组之间在基线特征方面未观察到显著差异。与VH组相比,LH组观察到中位手术时间有延长的趋势(75[范围,20 - 340]分钟对60[范围,30 - 140]分钟;P = 0.09),而与VH相比,LH与较短的住院时间和较少的失血量相关(P < 0.05)。VH手术期间发生了1例术中并发症(膀胱损伤);LH组未记录到术中并发症。在2级(或更严重)术后并发症方面未观察到差异(LH组40例中有1例[2.5%],VH组40例中有3例[7.5%];P = 0.61;比值比,3.1;95%可信区间,0.3 - 31.8),且未发生术后死亡。

结论

我们的研究结果表明LH不劣于VH。LH改善了接受良性子宫疾病手术的老年女性的术后病程。如果存在适当的适应症,不应仅基于年龄而拒绝LH手术。

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