Baxter Siyan, Sanderson Kristy, Venn Alison J, Blizzard C Leigh, Palmer Andrew J
Am J Health Promot. 2014 Jul-Aug;28(6):347-63. doi: 10.4278/ajhp.130731-LIT-395.
To determine the relationship between return on investment (ROI) and quality of study methodology in workplace health promotion programs.
Data were obtained through a systematic literature search of National Health Service Economic Evaluation Database (NHS EED), Database of Abstracts of Reviews of Effects (DARE), Health Technology Database (HTA), Cost Effectiveness Analysis (CEA) Registry, EconLit, PubMed, Embase, Wiley, and Scopus.
Included were articles written in English or German reporting cost(s) and benefit(s) and single or multicomponent health promotion programs on working adults. Return-to-work and workplace injury prevention studies were excluded.
Methodological quality was graded using British Medical Journal Economic Evaluation Working Party checklist. Economic outcomes were presented as ROI.
ROI was calculated as ROI = (benefits - costs of program)/costs of program. Results were weighted by study size and combined using meta-analysis techniques. Sensitivity analysis was performed using two additional methodological quality checklists. The influences of quality score and important study characteristics on ROI were explored.
Fifty-one studies (61 intervention arms) published between 1984 and 2012 included 261,901 participants and 122,242 controls from nine industry types across 12 countries. Methodological quality scores were highly correlated between checklists (r = .84-.93). Methodological quality improved over time. Overall weighted ROI [mean ± standard deviation (confidence interval)] was 1.38 ± 1.97 (1.38-1.39), which indicated a 138% return on investment. When accounting for methodological quality, an inverse relationship to ROI was found. High-quality studies (n = 18) had a smaller mean ROI, 0.26 ± 1.74 (.23-.30), compared to moderate (n = 16) 0.90 ± 1.25 (.90-.91) and low-quality (n = 27) 2.32 ± 2.14 (2.30-2.33) studies. Randomized control trials (RCTs) (n = 12) exhibited negative ROI, -0.22 ± 2.41(-.27 to -.16). Financial returns become increasingly positive across quasi-experimental, nonexperimental, and modeled studies: 1.12 ± 2.16 (1.11-1.14), 1.61 ± 0.91 (1.56-1.65), and 2.05 ± 0.88 (2.04-2.06), respectively.
Overall, mean weighted ROI in workplace health promotion demonstrated a positive ROI. Higher methodological quality studies provided evidence of smaller financial returns. Methodological quality and study design are important determinants.
确定工作场所健康促进项目的投资回报率(ROI)与研究方法质量之间的关系。
通过对国家卫生服务经济评价数据库(NHS EED)、效果评价摘要数据库(DARE)、卫生技术数据库(HTA)、成本效益分析(CEA)注册库、EconLit、PubMed、Embase、Wiley和Scopus进行系统文献检索获取数据。
纳入用英文或德文撰写的、报告了成本和效益以及针对在职成年人的单一或多组分健康促进项目的文章。排除重返工作岗位和工作场所伤害预防研究。
使用《英国医学杂志》经济评价工作组清单对方法学质量进行分级。经济结果以投资回报率表示。
投资回报率的计算方法为ROI =(项目效益 - 项目成本)/项目成本。结果按研究规模加权,并使用荟萃分析技术进行合并。使用另外两份方法学质量清单进行敏感性分析。探讨了质量得分和重要研究特征对投资回报率的影响。
1984年至2012年间发表的51项研究(61个干预组)包括来自12个国家9种行业类型的261,901名参与者和122,242名对照。各清单之间的方法学质量得分高度相关(r = 0.84 - 0.93)。方法学质量随时间推移有所提高。总体加权投资回报率[均值±标准差(置信区间)]为1.38±1.97(1.38 - 1.39),表明投资回报率为138%。在考虑方法学质量时,发现其与投资回报率呈负相关。高质量研究(n = 18)的平均投资回报率较小,为0.26±1.74(0.23 - 0.30),而中等质量(n = 16)的为0.90±1.25(0.90 - 0.91),低质量(n = 27)的为2.32±2.14(2.30 - 2.33)。随机对照试验(RCTs)(n = 12)的投资回报率为负,为 - 0.22±2.41( - 0.27至 - 0.16)。在准实验性、非实验性和模型研究中,财务回报越来越正向:分别为1.12±2.16(1.11 - 1.14)、1.61±0.91(1.56 - 1.65)和2.05±0.88(2.04 - 2.06)。
总体而言,工作场所健康促进的平均加权投资回报率显示出正的投资回报率。方法学质量较高的研究提供了财务回报较小的证据。方法学质量和研究设计是重要的决定因素。