Shinonaga Togo, Tsukamoto Masahiro, Miyaji Godai
Opt Express. 2014 Jun 16;22(12):14696-704. doi: 10.1364/OE.22.014696.
Titanium dioxide (TiO2) film is an important biomaterial used to improve the biocompatibility of titanium (Ti). We have used a film coating method with an aerosol beam and femtosecond laser irradiation to form periodic structures on biomaterials for control of the cell spreading. The control of cell spreading on biomaterials is important for the development of advanced biomaterials. In this study, nanostructures with periods of 130 and 230 nm were formed on a film using a femtosecond laser with wavelengths of 388 and 775 nm, respectively. The nanostructure period on the film was 30% of the laser wavelengths. Periods produced with wavelengths of 388 and 775 nm were calculated using a surface plasmon polariton (SPP) model and the experimental results for both wavelengths were in the range of the calculated periods, which suggests that the mechanism for the formation of the periodic nanostructures on the film with a femtosecond laser was due to the excitation of SPPs.
二氧化钛（TiO₂）薄膜是一种用于改善钛（Ti）生物相容性的重要生物材料。我们采用了一种气溶胶束和飞秒激光辐照的薄膜涂层方法，在生物材料上形成周期性结构以控制细胞铺展。控制生物材料上的细胞铺展对于先进生物材料的开发至关重要。在本研究中，分别使用波长为388和775 nm的飞秒激光在薄膜上形成了周期为130和230 nm的纳米结构。薄膜上的纳米结构周期为激光波长的30%。使用表面等离激元极化激元（SPP）模型计算了波长为388和775 nm时产生的周期，并且两种波长的实验结果都在计算出的周期范围内，这表明用飞秒激光在薄膜上形成周期性纳米结构的机制是由于SPP的激发。
