From the Department of Radiation Oncology, The First Hospital, Jilin University, Changchun, China.
Clin Nucl Med. 2014 Aug;39(8):755-7. doi: 10.1097/RLU.0000000000000503.
A 54-year-old woman presented with left axillary adenopathy for 6 months. Biopsy result was consistent with nodal metastases of breast carcinoma: estrogen receptor (negative), progesterone receptor (negative), and Her-2 (negative). The primary breast tumor, however, could not be detected on breast ultrasound, mammography, and magnetic resonance imaging. F-FDG PET/CT revealed a mildly FDG-avid nodule in her left breast, consistent with primary tumor. She received neoadjuvant chemotherapy followed by modified radical mastectomy. The case demonstrates the usefulness of FDG PET/CT in evaluating patients with breast cancer, even when the primary tumor remains undetected by other modalities.
一位 54 岁女性因左侧腋窝淋巴结肿大就诊，病史为 6 个月。活检结果符合乳腺癌淋巴结转移：雌激素受体（阴性）、孕激素受体（阴性）和 Her-2（阴性）。然而，乳腺超声、乳腺 X 线摄影和磁共振成像均未能检测到原发性乳腺肿瘤。18F-FDG PET/CT 显示其左侧乳腺有一个轻度 18F-FDG 摄取的结节，符合原发性肿瘤。患者接受新辅助化疗后行改良根治性乳房切除术。该病例表明 FDG PET/CT 对于评估乳腺癌患者具有重要作用，即使其他影像学方法仍未能检测到原发性肿瘤。
