18F-FDG PET/CT 评价乳腺癌不常见皮肤表现。

FDG PET/CT in evaluation of unusual cutaneous manifestations of breast cancer.

机构信息

From the *Department of Medicine, †Hematology/Oncology Section, ‡Nuclear Medicine Section, Department of Radiology, and §Anatomic Pathology Section, Department of Pathology, Medical College of Georgia at Georgia Regents University, Augusta, GA.

出版信息

Clin Nucl Med. 2015 Jan;40(1):e63-7. doi: 10.1097/RLU.0000000000000553.

DOI:10.1097/RLU.0000000000000553

PMID:25140546

Abstract

Cutaneous metastases of primary internal malignancies are rare, with an incidence of 0.7% to 10.4%. Cutaneous manifestations due to breast cancer are the most common metastases dermatologists observe, with a prevalence of 2.4% and an incidence of 23.9%. Presence of cutaneous metastases is usually a late event in disease progression, indicating grave prognosis. Recognition of cutaneous breast cancer metastases significantly alters therapeutic plans, especially when the disease was thought to be successfully cured. F-FDG PET CT imaging can detect cutaneous metastasis and sites of distant metastases and monitor response to therapy. We report 3 patients with cutaneous-predominant breast carcinoma seen by FDG PET/CT.

摘要

皮肤转移原发于内部恶性肿瘤较为罕见，发病率为 0.7%至 10.4%。皮肤科医生观察到的最常见的乳腺癌皮肤转移表现，发病率为 2.4%，发生率为 23.9%。皮肤转移的发生通常是疾病进展的晚期事件，提示预后不良。识别皮肤乳腺癌转移可显著改变治疗计划，尤其是当疾病被认为已成功治愈时。18F-FDG PET CT 成像可检测皮肤转移和远处转移部位，并监测治疗反应。我们报告了 3 例 FDG PET/CT 检查的皮肤为主型乳腺癌患者。