Köster Moritz, Friese Uwe, Schöne Benjamin, Trujillo-Barreto Nelson, Gruber Thomas
Institute of Psychology, University of Osnabrück, Osnabrück, Germany; Institute of Cognitive Science, University of Osnabrück, Osnabrück, Germany.
University Medical Center Hamburg-Eppendorf, Department of Neurophysiology and Pathophysiology, Hamburg, Germany.
Brain Res. 2014 Aug 19;1577:57-68. doi: 10.1016/j.brainres.2014.06.028. Epub 2014 Jun 27.
Recent findings indicate that phase-amplitude coupling between neuronal oscillations in the theta- (3-6 Hz) and the gamma-band (30-100 Hz) plays a functional role in memory processes. Here, using electroencephalography, we provide further evidence for coupling between prefrontal theta and parietal gamma during successful memory retrieval in the human brain. In a pictorial recognition task, the coupling between prefrontal theta phase and parietal gamma amplitude was quantified using the modulation index, 100-1500 ms after stimulus onset. Results show an increased coupling for remembered, as opposed to forgotten and new stimuli (i.e. a "recognition effect" and an "old/new effect"). Phase-amplitude coupling between the prefrontal theta phase and posterior gamma amplitudes is hypothesized to reflect long range communication between prefrontal control processes and the activation of posterior object representations accompanying mnemonic processing.
最近的研究结果表明，神经元在θ波（3 - 6赫兹）和γ波段（30 - 100赫兹）振荡之间的相位 - 振幅耦合在记忆过程中发挥着功能性作用。在此，我们使用脑电图技术，为人脑在成功记忆检索过程中前额叶θ波和顶叶γ波之间的耦合提供了进一步证据。在一个图像识别任务中，使用调制指数对刺激开始后100 - 1500毫秒期间前额叶θ波相位和顶叶γ波振幅之间的耦合进行了量化。结果显示，与被遗忘和新的刺激相比，被记住的刺激的耦合增加（即“识别效应”和“新旧效应”）。前额叶θ波相位和后顶叶γ波振幅之间的相位 - 振幅耦合被认为反映了前额叶控制过程与伴随记忆处理的后顶叶客体表征激活之间的长距离通信。
