胰腺内副脾：计算机断层扫描在与无功能胰腺神经内分泌肿瘤鉴别诊断中的应用可能性
Intrapancreatic accessory spleen: possibilities of computed tomography in differentiation from nonfunctioning pancreatic neuroendocrine tumor.
作者信息
Coquia Stephanie F, Kawamoto Satomi, Zaheer Atif, Bleich Karen B, Blackford Amanda L, Hruban Ralph H, Fishman Elliot K
机构信息
From the *Department of Radiology, †Division of Biostatistics and Bioinformatics, Sidney Kimmel Cancer Center, and ‡Department of Pathology, the Sol Goldman Pancreatic Center Research Center, Johns Hopkins Hospital, Baltimore, MD.
出版信息
J Comput Assist Tomogr. 2014 Nov-Dec;38(6):874-8. doi: 10.1097/RCT.0000000000000127.
OBJECTIVE
The aim of this study was to evaluate the ability of computed tomography (CT) in differentiating between intrapancreatic accessory spleen (IPAS) from pancreatic neuroendocrine tumor (PanNET).
METHODS
Eight IPASs and 12 PanNETs in the pancreatic tail were retrospectively evaluated by 2 radiologists. Readers assigned a diagnosis to each examination and evaluated for the presence or absence of 9 CT findings that may aid in the diagnosis.
RESULTS
Reader 1 had a sensitivity of 0.83 and a specificity of 1; reader 2 had a sensitivity of 0.78 and a specificity of 0.86. Three of the 9 CT findings were found to be statistically significant in IPASs: the lesion present along the pancreatic dorsal surface, the lesion demonstrating the same enhancement as the spleen on venous phase, and heterogeneous enhancement during arterial phase.
CONCLUSIONS
CT can be used to differentiate between IPAS and PanNET with good specificity and sensitivity. The IPAS mirrors the spleen's enhancement and is usually located along the dorsal surface of the pancreas.
目的
本研究旨在评估计算机断层扫描（CT）区分胰腺内副脾（IPAS）与胰腺神经内分泌肿瘤（PanNET）的能力。
方法
两名放射科医生对8例胰腺尾部的IPAS和12例胰腺尾部的PanNET进行回顾性评估。阅片者对每次检查进行诊断，并评估9项可能有助于诊断的CT表现的有无。
结果
阅片者1的敏感度为0.83，特异度为1；阅片者2的敏感度为0.78，特异度为0.86。9项CT表现中有3项在IPAS中具有统计学意义：病变位于胰腺背侧表面、病变在静脉期与脾脏表现出相同的强化以及在动脉期呈不均匀强化。
结论
CT可用于以良好的特异度和敏感度区分IPAS和PanNET。IPAS与脾脏强化相似，通常位于胰腺背侧表面。
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